Results 81 to 90 of about 19,033 (167)

GPR30在卵巢癌的亚细胞定位及临床意义

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】 研究GPR30在卵巢癌中的亚细胞定位及临床意义?【方法】 应用免疫组化技术检测我院2000-2010年的110例卵巢癌组织中GPR30的表达,分析GPR30与卵巢癌的临床病理特点的关系?同时应用流式分选技术和免疫荧光技术检测GPR30在卵巢癌的亚细胞定位? 【结果】 GPR30在62.7%的卵巢癌组织中表达,其中包括51例浆液性腺癌和4例黏液性腺癌中(P = 0.102)?肿瘤残余组(R1,33/45)中GPR30表达率高于无残留组(R0,34/65),具有统计学差异(P = 0 ...
doaj  

Aberrant STYK1 expression in ovarian cancer tissues and cell lines

Journal of Ovarian Research, 2009
Background Overexpression of STYK1, a putative serine/threonine and tyrosine receptor protein kinase has been shown to confer tumorigenicity and metastatic potential to normal cells injected into nude mice. Mutation of a tyrosine residue in the catalytic
Jackson Kesmic A, Oprea Gabriela, Handy Jeffrey, Kimbro K Sean   +3 more
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GPR30 mediates anorectic estrogen-induced STAT3 signaling in the hypothalamus

Metabolism, 2014
Estrogen plays an important role in the control of energy balance in the hypothalamus. Leptin-independent STAT3 activation (i.e., tyrosine(705)-phosphorylation of STAT3, pSTAT3) in the hypothalamus is hypothesized as the primary mechanism of the estrogen-induced anorexic response.
Obin, Kwon, Eun Seok, Kang, Insook, Kim, Sora, Shin, Mijung, Kim, Somin, Kwon, So Ra, Oh, Young Soo, Ahn, Chul Hoon, Kim   +8 more
openaire   +3 more sources

Intracellular Distribution and Involvement of GPR30 in the Actions of E2 on C2C12 Cells.

Journal of cellular biochemistry, 2015
Fil: Ronda, Ana Carolina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico Bahia Blanca. Instituto de Ciencias Biologicas y Biomedicas del Sur; Argentina.
Ronda, Ana Carolina, Boland, Ricardo Leopoldo   +1 more
openaire   +3 more sources

Effects of estrogen receptor GPR30 agonist G1 on neuronal apoptosis and microglia polarization in traumatic brain injury rats

Chinese Journal of Traumatology, 2018
Purpose: To investigate the effects of estrogen G protein-coupled receptor 30 (GPR30) agonist G1 on hippocampal neuronal apoptosis and microglial polarization in rat traumatic brain injury (TBI).
Meng-Xian Pan, Jun-Chun Tang, Rui Liu, Yu-Gong Feng, Qi Wan   +4 more
doaj   +1 more source

The role of GRK2 in hypertension and regulation of GPR30 [PDF]

, 2012
In the hypertensive state, the expression of G protein-coupled receptor kinase 2 (GRK2) level is elevated. On the other hand, the expression of GPR30, a recently discovered GPCR is greatly impaired. The current study focuses on investigating the roles of these two proteins in regulating G protein signaling under the normal and hypertensive states ...
openaire  

AMPK Phosphorylation Effect of Genistein Is Independent of GPR30 [PDF]

Current Developments in Nutrition, 2020
Sarai Vásquez-Reyes, Ariana Vargas-Castillo, Jose C Crispin, Florencia Rosetti, Nimbe Torres, Alfredo Ulloa-Aguirre, Armando Tovar   +6 more
openaire   +1 more source

Ipriflavone promotes proliferation and osteogenic differentiation of periodontal ligament cells by activating GPR30/PI3K/AKT signaling pathway

Drug Design, Development and Therapy, 2018
Yuanyuan Han,1,2 Xuxia Wang,2,3 Dan Ma,1,2 Xiaoxiao Wu,1,2 Panpan Yang,1,2 Jun Zhang1,2 1Department of Orthodontics, Faculty of Stomatology, Shandong University, Jinan, 2Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of ...
Han Y, Wang X, Ma D, Wu X, Yang P, Zhang J   +5 more
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Zearalenone Induces Gap Junction Damage in Ovine Ovarian Granulosa Cells by Upregulating GPR30 and Activating the Oxidative Stress-NLRP3 Inflammasome Axis. [PDF]

Biomolecules
Pang X, Zhang D, Duan H, Yan Z, Du X, Zhao L, Yang J, Xue L, Wang Y, He Y.   +9 more
europepmc   +1 more source

The Crucial Role of GPR30 and Histone Crotonylation during the Inflammatory Repair Process in Ligature-Induced Periodontitis. [PDF]

Acta Histochem Cytochem
Fidya, Ishizuka T, Kubota T, Kai K, Hishikawa Y.   +4 more
europepmc   +1 more source