Results 61 to 70 of about 1,699 (149)
Virology Journal, 2021 Background African swine fever virus (ASFV) is a highly lethal virus that can infect porcine alveolar macrophages (PAMs). Since ASFV, China has dealt with a heavy blow to the pig industry.
Bo Yang +13 more
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Animals, 2021 The immune response to a viral antigen causes inflammatory cell infiltration to the tissue, which creates a suitable environment for the replication of the virus in macrophages, and the recruitment of more monocytes to the site of infection, or latently ...
Joanna Pławińska-Czarnak +6 more
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Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi +4 more
wiley +1 more source
GPR37 Modulates Remyelination Following Demyelinating Injury
The Journal of NeuroscienceGPR37 has been recognized as a negative regulator of oligodendrocyte myelination. However, its role in demyelination recovery remains unclear. To examine the function of GPR37 in remyelination, we compared wild-type and GPR37-deficient mice of either sex after focal (lysolecithin) or global (cuprizone) toxin-induced demyelination ...
Hajbi Karasik, Renana +6 more
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Expression of prosaposin and its receptors in the rat cerebellum after kainic acid injection
IBRO Reports, 2017 Prosaposin (PSAP), a highly conserved glycoprotein, is a precursor of saposins A–D. Accumulating evidence suggests that PSAP is a neurotrophic factor that induces differentiation and prevents death in a variety of neuronal cells through the active region
Xuan Li +9 more
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Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao +4 more
wiley +1 more source
GPR37 and GPR37L1 differently interact with dopamine 2 receptors in live cells
Neuropharmacology, 2019 Receptor-receptor interactions are essential to fine tune receptor responses and new techniques enable closer characterization of the interactions between involved proteins directly in the plasma membrane. Fluorescence cross-correlation spectroscopy (FCCS), which analyses concurrent movement of bound molecules with single-molecule detection limit, was ...
Hertz, E. +3 more
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Frontiers in Cell and Developmental Biology, 2023 Most mammals tolerate exposure to hypobaric hypoxia poorly as it may affect multiple regulatory mechanisms and inhibit cell proliferation, promote apoptosis, limit tissue vascularization, and disrupt the acid–base equilibrium.
Yun-Hua Ji +13 more
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Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy
Advanced Science, Volume 13, Issue 39, 13 July 2026.Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang +5 more
wiley +1 more source
PLoS ONE, 2020 Neurotrophic factor prosaposin (PS) is a precursor for saposins A, B, C, and D, which are activators for specific sphingolipid hydrolases in lysosomes. Both saposins and PS are widely contained in various tissues.
Joji Kunihiro +11 more
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