Results 41 to 50 of about 4,181 (199)
BMC Genomics, 2011 Background Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH.
Sutcliffe Margaret +13 more
doaj +1 more source
FEBS Open Bio, 2019 Due to its exceptionally small genome size and protogynous hermaphroditism, Monopterus albus has been proposed as a model for vertebrate sexual development.
Ti‐Lin Yi +2 more
doaj +1 more source
GPR54 (Kiss1R) immunostaining in the Placenta.
, 2013 Fig. 2 (a–c) demonstrate GPR54 immunohistochemistry with individual villous cytotrophoblast cell staining for GPR 54 (red) in the placental villus (pv) (Fig. 2a). Fig. 2b shows GPR54 (red) immunostaining of villous cytotrophoblasts (vCT), cytotrophoblast
Robert Millar (413075) +3 more
core +1 more source
Hypothalamic KiSS1/GPR54 Gene Expressions and Luteinizing Hormone Plasma Secretion in Morphine Treated Male Rats [PDF]
International Journal of Fertility and Sterility, 2018 Background: The inhibitory effects of morphine and the stimulatory influence of kisspeptin signaling have been demonstrated on gonadotropin releasing hormone (GnRH)/luteinizing hormone (LH) release.
Homayoun Khazali +2 more
doaj +1 more source
Dependence of fertility on kisspeptin–Gpr54 signaling at the GnRH neuron [PDF]
Nature Communications, 2013 Signaling between kisspeptin and its receptor, G-protein-coupled receptor 54 (Gpr54), is now recognized as being essential for normal fertility. However, the key cellular location of kisspeptin-Gpr54 signaling is unknown. Here we create a mouse with a GnRH neuron-specific deletion of Gpr54 to assess the role of gonadotropin-releasing hormone (GnRH ...
Milen, Kirilov +7 more
openaire +2 more sources
The genes associated with gonadotropin-releasing hormone-dependent precocious puberty [PDF]
Korean Journal of Pediatrics, 2012 Human puberty is a complex, coordinated biological process with multiple levels of regulations. The timing of puberty varies greatly in children and is influenced by both environmental and genetic factors.
Jin Soon Hwang
doaj +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.This study explores the potential of hyperoside to activate the estrogen‐PI3K/VEGF axis, thereby suppressing oxidative stress and enhancing osteogenic differentiation to mitigate osteoporosis. The initial proposal of the estrogen‐PI3K/VEGF signaling pathway axis as a potential therapeutic approach for osteoporosis.
Shuo Wang +8 more
wiley +1 more source
Interactions of GPR54 and GPR147 receptors with RF-amide ligands [PDF]
, 2014 Includes bibliographical references.G protein-coupled receptors play a key role in cellular signaling by transducing extracellular signals via G proteins to elicit intracellular responses.
Hendrikse, Megan
core +1 more source
Novel genetic polymorphisms in caprine GPR54 gene associated with reproductive functions
Indian Journal of Animal Sciences, 2014 The objective of this study was to characterize caprine GPR54 gene, a key mediator of molecular mechanism of reproduction (puberty and prolificacy) in mammals.
A MAITRA +3 more
doaj +1 more source
Expressions of Kisspeptin System and Ki‐67 in the Reproductive Tissues of Cyclic Bitches
Reproduction in Domestic Animals, Volume 61, Issue 4, April 2026.ABSTRACT Kisspeptin is a peptide that plays a pivotal role in the central regulation of gonadotropins. It is regarded as a key regulator of reproductive processes, including follicular and luteal development and endometrial remodelling. The objective of this study was to investigate the expression of KISS1, its receptor KISS1R and the proliferation ...
Özgecan Korkmaz Ağaoğlu +4 more
wiley +1 more source