Results 71 to 80 of about 4,400 (198)
Journal of Neuroendocrinology, Volume 37, Issue 8, August 2025.Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley +1 more source
Groundwater Flooding of Superficial Gravels in an Urbanized Catchment
Journal of Flood Risk Management, Volume 18, Issue 2, June 2025.ABSTRACT Groundwater behavior in superficial gravel aquifers is globally poorly understood, especially across urban regions where drinking water is sourced from elsewhere. This study focuses on one such region around Staines, SE UK, where local River Terrace Gravels form a thin (< 10 m) superficial aquifer.
Jonathan D. Paul +3 more
wiley +1 more source
In vitro and in vivo effects of kisspeptin antagonists p234, p271, p354, and p356 on GPR54 activation. [PDF]
PLoS ONE, 2017 Kisspeptins (KPs) and their receptor (GPR54 or KiSS1R) play a key-role in regulation of the hypothalamic-pituitary-gonadal axis and are therefore interesting targets for therapeutic interventions in the field of reproductive endocrinology. As dogs show a
C H J Albers-Wolthers +10 more
doaj +1 more source
A GPR54 -Activating Mutation in a Patient with Central Precocious Puberty [PDF]
New England Journal of Medicine, 2008 Gonadotropin-dependent, or central, precocious puberty is caused by early maturation of the hypothalamic-pituitary-gonadal axis. In girls, this condition is most often idiopathic. Recently, a G protein-coupled receptor, GPR54, and its ligand, kisspeptin, were described as an excitatory neuroregulator system for the secretion of gonadotropin-releasing ...
Milena Gurgel, Teles +9 more
openaire +2 more sources
, 2018 Kisspeptin-10 (KP-10) acts as a tumor metastasis suppressor via its receptor, G-protein-coupled receptor 54 (GPR54). The KP-10-GPR54 system plays an important role in embryonic kidney development.
Kyeong-Min Kim +3 more
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Journal of Neuroendocrinology, Volume 37, Issue 5, May 2025.Abstract Kisspeptinergic signaling is well‐established as crucial for the regulation of reproduction, but its potential broader role in brain function is less understood. This study investigates the distribution and chemotyping of kisspeptin‐expressing neurons within the mouse brain.
Vito S. Hernández +7 more
wiley +1 more source
The kisspeptin and GPR54 ligand-receptor pair in autocrine and endocrine signalling in cancer
, 2009 Kisspeptins and their receptor, GPR54, mediate sex hormone release through stimulation of the hypothalamic-pituitary-gonadal axis and have been implicated as metastasis suppressors.
Prentice, Leah Marie
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundKisspeptin‐10 (KP‐10), a potent vasoconstrictor and inhibitor of angiogenesis, and its receptor, GPR54, have currently received much attention in relation to pre‐eclampsia.
Kengo Sato +14 more
doaj +1 more source
Reproductive Biology and Endocrinology, 2019 Background Excessive gestational weight gain (GWG), which is associated with adverse long-term effects on the health of the offspring, has become a major clinical problem.
Zhiyang Zhou +5 more
doaj +1 more source
The Novel Role of Kisspeptin and GPR54 in Mice Reproduction
, 2013 近年研究指出Kisspeptin與其受體GPR54在動物的生殖生理調控扮演重要的角色。Kisspeptin為Kiss1基因的蛋白質產物，其生殖生理之功能主在刺激GnRH神經元興奮進而調控下游的下視丘-腦垂腺-性腺軸及其所引發的相關生理調控。目前已有報告提出Kiss-1與Gpr54基因在動物多種器官組織均有表現，然而其所調控的生理功能則尚未完全被瞭解。因此，本研究將探討kisspeptin與GPR54在小鼠睪丸與卵巢組織之表現性狀及其可能扮演之功能。 本研究以成年ICR小鼠做為實驗動物 ...
許孟傑, Hsu, Meng-Chieh
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