Results 271 to 280 of about 40,571 (376)

hCeO2 Promotes M2 Polarization and Modulates the SLC7A11/GSH/GPX4 Axis to Attenuate Macrophage Ferroptosis for Inflammatory Wound Repair

Shiyu Sun, Dan Luo, Kai Song, Jinpei Cui, Jie Liu, Xue Li   +5 more
openalex   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Computational characterization of GRP78 binding sites on mitochondrial GPX4: implications for targeting ferroptosis in triple-negative breast cancer. [PDF]

Sci Rep
Youssef DG, Elfiky AA.
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Ferroptosis in Myocardial Fibrosis: Mechanisms and Therapeutic Insights. [PDF]

Antioxidants (Basel)
Lin X, Li W, Ye J, Li L.
europepmc   +1 more source

HSP27 stabilizes GPX4 and inhibits radiation-induced ferroptosis via blocking Hsc70-mediated chaperone-mediated autophagy in cervical cancer

Guanghui Cheng, Shanshan Song, Jinbao Wang, Ning Zhang, Baocai Liu, Qian Wang, Yunbo Chi, Zhaoming Zhang, Hongfu Zhao, Zhipeng Zhao, Dapeng Xi, Xinyue Yu, Kun Zou   +12 more
openalex   +1 more source

Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8 ⁺ T cell function and its impact against pancreatic ductal adenocarcinoma [PDF]

Wei Wei, Linqing Tian, Xiaoyan Zheng, Lei Zhong, Yuan Chen, Hui Dong, Guibing Zhang, Shibing Wang, Xiangmin Tong   +8 more
openalex   +1 more source

Hippo Pathway Drives Durable Non‐Cell‐Autonomous Ferroptosis Resistance in Lung Cancer

Cancer Science, EarlyView.
YAP/TAZ, key effectors in lung cancer progression, paradoxically sensitize tumor cells to ferroptosis. This study reveals that YAP/TAZ‐low cells confer non‐cell‐autonomous, GCH1‐mediated durable ferroptosis resistance to neighboring YAP/TAZ‐high cells via a soluble factor, highlighting a Hippo pathway‐linked mechanism of tumor adaptation and survival ...
Mohamed Fathi Saleh, Akihiro Nita, Yudai Ohta, Aya Kobayashi, Hao Li, Yasuhisa Sakamoto, Toshiro Moroishi   +6 more
wiley   +1 more source

Co-targeting ferroptosis and immune evasion through small molecules in breast cancer. [PDF]

J Transl Int Med
Zhou J, Yang W, Tang H, Zou Y, Zhou Z, Peng C, Peng F.   +6 more
europepmc   +1 more source