The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]
Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B +7 more
core +1 more source
Multiquadrant Subtenon Triamcinolone Injection for Acute Corneal Graft Rejection: A Case Report
Background: We report a case of reversal of an acute corneal graft rejection following multiquadrant subtenon triamcinolone injection. Case Presentation: A 19-year-old woman who had acute corneal graft rejection failed to show resolution of the graft ...
Sunali Goyal, Sami H. Uwaydat
doaj +1 more source
A clinicopathological study of human liver allograft recipients harboring preformed IgG lymphocytotoxic antibodies [PDF]
Twenty‐six adult patients with preformed IgG donor lymphocytotoxic antibodies received primary liver allografts under FK 506 immunosuppression. The effect of the crossmatch‐positive state on early graft function and on the immunopathological and ...
Batts +40 more
core +1 more source
Transcriptional Perturbations in Graft Rejection [PDF]
Understanding the regulatory interplay of relevant microRNAs (miRNAs) and messenger RNAs (mRNAs) in the rejecting allograft will result in a better understanding of the molecular pathophysiology of alloimmune injury.One hundred sixty-seven allograft biopsies, with (n = 47) and without (n = 120) central histology for Banff scored acute rejection (AR ...
Vitalone, Matthew J +5 more
openaire +4 more sources
Cause and timing of first allograft failure in orthotopic liver transplantation: A study of 177 consecutive patients [PDF]
The cause and timing of first liver allograft failure was evaluated in 177 patients who underwent a second liver transplant between January 1984 and December 1988.
Busuttil +22 more
core +1 more source
Background. The presence of donor-specific antibodies (DSAs) against HLA before kidney transplantation has been variably associated with decreased long-term graft survival.
Michiel G. H. Betjes +5 more
doaj +1 more source
What have we learned about primary liver transplantation under tacrolimus immunosuppression? - Long-term follow-up of the first 1000 patients [PDF]
Objective: To summarize the long-term efficacy and safety of tacrolimus in orthotopic liver transplant (OLT) recipients, as well as to examine the factors that influence long-term morbidity and mortality rates. Background: Tacrolimus (FK506, Prograf) was
Abu-Elmagd, K +6 more
core +2 more sources
Non-invasive monitoring of renal transplant recipients: Urinary excretion of soluble adhesion molecules and of the complement-split product C4d [PDF]
Background: The number of inducible adhesion molecules known to be involved in cell-mediated allograft rejection is still increasing. In addition, recent data describe complement activation during acute humoral allograft rejection.
Friedrich, N. +5 more
core +1 more source
Objective: We sought to assess the potential association between history of bariatric surgery and graft rejection among solid organ transplant (SOT) recipients.
Claire R. Harrington +7 more
doaj +1 more source
Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin®) [PDF]
Modifications in the timing and dosage of immunosuppression can ameliorate the morbidity and mortality that has prevented widespread use of intestinal transplantation (ITx) in children.
Abu-Elmagd, K +8 more
core +1 more source

