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Diagnostic value of miRNA-101 and miRNA-27 in acute heart transplant rejection
Objective: to determine the diagnostic value of miRNA-101 and miRNA-27 expression levels for acute hearttransplant rejection. Materials and methods. The study enrolled 46 heart recipients, among whom were 36 men (78.3%); the average age of recipients was
D. A. Velikiy+5 more
doaj +1 more source
Immunopathogenesis of corneal graft rejection
The most common cause of corneal graft failure is corneal graft rejection (CGR). Although cornea is one of the immune-privileged sites, it can still get a rejection episode due to a breach in its natural protective mechanism. Both anatomical and structural properties of cornea and anterior chamber contribute toward its immune tolerance.
Prafulla Kumar Maharana+7 more
openaire +3 more sources
Acute Corneal Endothelial Graft Rejection With Coinciding COVID-19 Infection
Purpose: To report a case of acute corneal endothelial graft rejection with the concurrent onset of coronavirus disease 2019 (COVID-19) symptoms. Observations: A 31-year-old African American woman with a history of asthma, sleep apnea, obesity (BMI of 40)
Sierra X. Jin, V. Juthani
semanticscholar +1 more source
Graft rejection in component keratoplasty
Among the various indications for keratoplasty, failed graft is one of the commonest indications in many published series. It is well known that the major cause of graft failure is endothelial rejection. In the last two decades, there has been a major paradigm shift in the surgical management of corneal diseases, and component keratoplasty has emerged ...
Rashmi Deshmukh+3 more
openaire +3 more sources
Organ transplantation is the main treatment for end-stage organ failure, which has rescued tens of thousands of lives. Immune rejection is the main factor affecting the survival of transplanted organs.
Kunli Zhang+11 more
doaj +1 more source
The impact of early acute rejection on kidney graft survival after repeat kidney transplantation
Introduction. Despite the improvements in immunosuppressive therapy, the growing number of repeat kidney transplantations and associated risks of acute rejection make it relevant to assess the impact of early acute rejection on a long-term kidney graft ...
A. V. Pinchuk+5 more
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Optimal Acceptance of Incompatible Kidneys [PDF]
Incompatibility between patient and donor is a major barrier in kidney transplantation (KT). The increasing shortage of kidney donors has driven the development of desensitization techniques to overcome this immunological challenge. Compared with compatible KT, patients undergoing incompatible KTs are more likely to experience rejection, infection ...
arxiv +1 more source
Transcriptional Perturbations in Graft Rejection [PDF]
Understanding the regulatory interplay of relevant microRNAs (miRNAs) and messenger RNAs (mRNAs) in the rejecting allograft will result in a better understanding of the molecular pathophysiology of alloimmune injury.One hundred sixty-seven allograft biopsies, with (n = 47) and without (n = 120) central histology for Banff scored acute rejection (AR ...
Vitalone, Matthew J+5 more
openaire +4 more sources
The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]
Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B+7 more
core +1 more source
Multiquadrant Subtenon Triamcinolone Injection for Acute Corneal Graft Rejection: A Case Report
Background: We report a case of reversal of an acute corneal graft rejection following multiquadrant subtenon triamcinolone injection. Case Presentation: A 19-year-old woman who had acute corneal graft rejection failed to show resolution of the graft ...
Sunali Goyal, Sami H. Uwaydat
doaj +1 more source