Results 41 to 50 of about 1,013,409 (339)

Approaches toward enhancing survival probability following deep anterior lamellar keratoplasty

Therapeutic Advances in Ophthalmology, 2020
The greatest advantage of deep anterior lamellar keratoplasty over full-thickness corneal transplantation is the elimination of graft failure caused by endothelial rejection.
Sepehr Feizi, Amir A Azari
doaj   +1 more source

Impaired Function of Peripherally Induced Regulatory T Cells in Hosts at High Risk of Graft Rejection

Scientific Reports, 2016
Regulatory T cells (Tregs) are crucial for allograft survival. Tregs can be divided into thymus-derived natural Tregs (tTregs) and peripherally-derived induced Tregs (pTregs).
Takenori Inomata, Jing Hua, A. Di Zazzo, R. Dana   +3 more
semanticscholar   +1 more source

HLA Antibody Incompatible Renal Transplantation: Long-term Outcomes Similar to Deceased Donor Transplantation

Transplantation Direct, 2021
Background. HLA incompatible renal transplantation still remains one of best therapeutic options for a subgroup of patients who are highly sensitized and difficult to match but not much is known about its long-term graft and patient survival.
Nithya Krishnan, MD, FRCP, Aisha Abimbola, MSc, Nandhini Machan, MSc, Sunil Daga, PhD, FRCP, Kishore Gopalakrishnan, MBBS, FRCPath, ForTai Lam, MD, FRCS, LamChin Tan, MD, FRCS, Habib Kashi, MD, FRCS, Christopher Imray, MD, FRCS, Daniel Zehnder, PhD, FRCP, Claire Collins, BSc, Rebecca Curtis, BSc, Robert Higgins, MD, FRCP, Natasha Khovanova, PhD, David Briggs, PhD   +14 more
doaj   +1 more source

Graft rejection – endogenous or allogeneic?

Immunology, 2012
SummaryThe presence and persistence of alloantigen is necessary for graft‐specific T‐cell‐mediated immunity. However, specificity comprises only a single facet of an extremely complex process. Evidence is accruing to suggest that immunogenicity could be manipulated by endogenous ligands released during tissue injury.
Fildes, James, Critchley, William R., Fildes, James E.   +2 more
openaire   +5 more sources

Macrophage subpopulations and their impact on chronic allograft rejection versus graft acceptance in a mouse heart transplant model

American Journal of Transplantation, 2018
Macrophages infiltrating the allografts are heterogeneous, consisting of proinflammatory (M1 cells) as well as antiinflammatory and fibrogenic phenotypes (M2 cells); they affect transplantation outcomes via diverse mechanisms.
Yue Zhao, Song Chen, P. Lan, Chenglin Wu, Yaling Dou, Xiang Xiao, Zhiqiang Zhang, L. Minze, Xiaoshun He, Wenhao Chen, Xian C. Li   +10 more
semanticscholar   +1 more source

Risk Factors of Rejection in Renal Transplant Recipients: A Narrative Review

Journal of Clinical Medicine, 2022
Multiple factors influence graft rejection after kidney transplantation. Pre-operative factors affecting graft function and survival include donor and recipient characteristics such as age, gender, race, and immunologic compatibility.
H. Oweira, Ali Ramouz, O. Ghamarnejad, E. Khajeh, Sadeq Ali-Hasan-Al-Saegh, Rajan Nikbakhsh, C. Reissfelder, N. Rahbari, A. Mehrabi, M. Sadeghi   +9 more
semanticscholar   +1 more source

Unexplained Graft Dysfunction after Heart Transplantation—Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report

Cardiology Research and Practice, 2010
In the current era of immunosuppressive medications there is increased observed incidence of graft dysfunction in the absence of known histological criteria of rejection after heart transplantation.
Khurram Shahzad, Martin Cadeiras, Kotaro Arai, Dmitry Abramov, Elizabeth Burke, Mario C. Deng   +5 more
doaj   +1 more source

Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study

PLoS Medicine, 2017
Background Graft-derived cell-free DNA (GcfDNA), which is released into the blood stream by necrotic and apoptotic cells, is a promising noninvasive organ integrity biomarker.
E. Schütz, A. Fischer, J. Beck, M. Harden, M. Koch, Tilo Wuensch, M. Stockmann, B. Nashan, O. Kollmar, J. Matthaei, P. Kanzow, P. Walson, J. Brockmöller, M. Oellerich   +13 more
semanticscholar   +1 more source

Descemet's membrane endothelial keratoplasty (DMEK) rejection following COVID-19 infection: A case report

American Journal of Ophthalmology Case Reports, 2021
Purpose: To report the first known case of Descemet's Membrane Endothelial Keratoplasty (DMEK) graft rejection following COVID19 infection. Observation: A 60-year-old woman with a history of DMEK for Fuch's dystrophy, presented with redness and vision ...
Karen Bitton, Mathieu Dubois, Romain Courtin, Christophe Panthier, Damien Gatinel   +4 more
doaj  

Immunosuppressants for the prophylaxis of corneal graft rejection after penetrating keratoplasty.

Cochrane Database of Systematic Reviews, 2015
BACKGROUND Penetrating keratoplasty is a corneal transplantation procedure in which a full-thickness cornea from the host is replaced by a graft from a donor.
Minawaer Abudou, Taixiang Wu, J. Evans, Xueyi Chen   +3 more
semanticscholar   +1 more source