Results 41 to 50 of about 1,018,553 (196)

Killer immunoglobulin-like receptor (KIR) and HLA genotypes affect the outcome of allogeneic kidney transplantation. [PDF]

PLoS ONE, 2012
BACKGROUND: Recipient NK cells may detect the lack of recipient's (i.e., self) HLA antigens on donor renal tissue by means of their killer cell immunoglobulin-like receptors (KIRs).
Izabela Nowak, Maria Magott-Procelewska, Agnieszka Kowal, Maciej Miazga, Marta Wagner, Wanda Niepiekło-Miniewska, Małgorzata Kamińska, Andrzej Wiśniewski, Edyta Majorczyk, Marian Klinger, Wioleta Łuszczek, Andrzej Pawlik, Rafał Płoski, Ewa Barcz, David Senitzer, Piotr Kuśnierczyk   +15 more
doaj   +1 more source

Deciphering the impact of senescence in kidney transplant rejection: An integrative machine learning and multi-omics analysis via bulk and single-cell RNA sequencing.

PLoS ONE
BackgroundThe demographic shift towards an older population presents significant challenges for kidney transplantation (KTx), particularly due to the vulnerability of aged donor kidneys to ischemic damage, delayed graft function, and reduced graft ...
Xihao Shen, Jiyue Wu, Feilong Zhang, Qing Bi, Zejia Sun, Wei Wang   +5 more
doaj   +1 more source

Resident memory T cells form during persistent antigen exposure leading to allograft rejection

Science immunology, 2021
Recipient effector T cells differentiate into functional tissue-resident memory T cells, causing graft rejection after kidney transplantation. Memories of rejection Long-term graft survival after organ transplantation can be hindered by immune-mediated ...
Khodor I. Abou-Daya, R. Tieu, Daqiang Zhao, R. Rammal, F. Sacirbegovic, Amanda L. Williams, W. Shlomchik, M. Oberbarnscheidt, Fadi G Lakkis   +8 more
semanticscholar   +1 more source

Case Report: A Case of Acute Cellular Rejection Due to Atopic Dermatitis Exacerbation 3 Years After Heart Transplantation

Frontiers in Immunology, 2021
BackgroundLittle evidence has been presented about the association between previous atopic/allergic disease and graft rejection after solid organ transplantation. Thus, we present a case wherein acute cellular rejection (ACR) after heart transplantation (
Nobutaka Kakuda, Eisuke Amiya, Eisuke Amiya, Masaru Hatano, Masaru Hatano, Hisataka Maki, Chie Bujo, Masaki Tsuji, Koichi Narita, Kanna Fujita, Junichi Ishida, Minoru Ono, Issei Komuro   +12 more
doaj   +1 more source

Markers of acute rejection and graft acceptance in liver transplantation.

World Journal of Gastroenterology, 2015
The evaluation of the immunosuppression state in liver transplanted patients is crucial for a correct post-transplant management and a major step towards the personalisation of the immunosuppressive therapy.
G. Germani, K. Rodríguez-Castro, F. Russo, M. Senzolo, A. Zanetto, A. Ferrarese, P. Burra   +6 more
semanticscholar   +1 more source

Keratoplasty Rejection After the BNT162b2 messenger RNA Vaccine

Cornea, 2021
Purpose: The aim of this report was to report 2 patients who presented with acute corneal graft rejection 2 weeks after receiving the BNT162b2 messenger RNA (mRNA) vaccine for severe acute respiratory syndrome coronavirus 2. Methods: Case report. Results:
L. Wasser, E. Roditi, D. Zadok, Liron Berkowitz, Y. Weill   +4 more
semanticscholar   +1 more source

Cytokines in Clinical and Experimental Transplantation

Mediators of Inflammation, 1994
Allograft rejection is a complex process, which requires interactions between different cell types and a variety of soluble factors, such as cytokines. In this review we discuss the role of cytokines in the induction and effector phases of the rejection ...
Ann C. T. M. Vossen, Huub F. J. Savelkoul   +1 more
doaj   +1 more source

THE ROLE OF PROTOCOL BIOPSIES IN EARLY PERIOD AFTER KIDNEY TRANSPLANTATION

Вестник трансплантологии и искусственных органов, 2010
46 protocol graft biopsies with the subsequent histological examination were performed in 39 patients after kidney transplantation. In 20 patients with stable graft function acute subclinical rejection were revealed in 12 (60%) with the following steroid
V. A. Suhorukov, Y. L. Yushinskis, I. Shtrumfa, R. L. Rozental   +3 more
doaj   +1 more source

Subclass analysis of donor HLA‐specific IgG in antibody‐incompatible renal transplantation reveals a significant association of IgG4 with rejection and graft failure

Transplant International, 2015
Donor HLA‐specific antibodies (DSAs) can cause rejection and graft loss after renal transplantation, but their levels measured by the current assays are not fully predictive of outcomes.
N. Khovanova, S. Daga, Torgyn Shaikhina, N. Krishnan, James Jones, D. Zehnder, D. Mitchell, R. Higgins, D. Briggs, D. Lowe   +9 more
semanticscholar   +1 more source

Rejeição de transplante de córnea Corneal Transplant Rejection

Revista Brasileira de Oftalmologia, 2008
A rejeição do transplante de córnea é um processo imunológico celular de ataque a córnea transplantada que pode resultar em sua descompensação. É a causa mais comum de falência de transplantes.
Dácio Carvalho Costa, Newton Kara-José
doaj   +1 more source