Use of donor serum to prevent passive transfer of hyperacute rejection [PDF]
, 1994 Organ transplantation in presensitized recipients continues to be contraindicated for heart and kidney recipients due to the risk of hyperacute rejection, which has no known treatment at this time.
Burlingham, William J. +4 more
core +1 more source
Graft-infiltrating host dendritic cells play a key role in organ transplant rejection
Nature Communications, 2016 Successful engraftment of organ transplants has traditionally relied on preventing the activation of recipient (host) T cells. Once T-cell activation has occurred, however, stalling the rejection process becomes increasingly difficult, leading to graft ...
Quan Zhuang +15 more
semanticscholar +1 more source
NK Cells: Not Just Followers But Also Initiators of Chronic Vascular Rejection
Transplant InternationalChronic graft rejection represents a significant threat to long-term graft survival. Early diagnosis, understanding of the immunological mechanisms and appropriate therapeutic management are essential to improve graft survival and quality of life for ...
Mathilde Chambon +3 more
doaj +1 more source
Chronic allograft rejection: A significant hurdle to transplant success
Burns & Trauma, 2014 The state-of-the-art immunosuppression drugs do not ensure indefinite transplant survival, and most transplants are continuously lost to chronic rejection even years posttransplantation.
Malgorzata Kloc, Rafik M Ghobrial
doaj +1 more source
Lack of Association between Interleukin-10 Gene Polymorphisms and Graft Rejection Risk in Kidney Transplantation Recipients: A Meta-Analysis. [PDF]
PLoS ONE, 2015 Interleukin-10 (IL-10) is an important immunomodulatory cytokine. Several studies focused the association between IL-10 promoter gene polymorphisms and graft rejection risk in kidney transplantation recipients.
Jiachuan Xiong +8 more
doaj +1 more source
BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT. [PDF]
, 2014 The genetic background of donor and recipient is an important factor determining the outcome of allogeneic hematopoietic SCT (allo-HSCT). We applied whole-genome analysis to investigate genetic variants - other than HLA class I and II - associated with ...
Andreani M +13 more
core +1 more source
Bipartite Graft I: Dulmage-Mendelsohn Decomposition for Combs [PDF]
arXiv, 2020 We provide an analogue of the Dulmage-Mendelsohn decomposition for a class of grafts known as comb-bipartite grafts. The Dulmage-Mendelsohn decomposition in matching theory is a classical canonical structure theorem for bipartite graphs. The substantial part of this classical theorem resides in bipartite graphs that are factorizable, that is, those ...
arxiv
Predicting Corneal Graft Rejection by Confocal Microscopy
Cornea, 2015 Purpose: This study aims at estimating corneal healing by activated keratocyte (AK) counting with in vivo confocal microscopy after perforating keratoplasty (PK). It assesses the value of AK counting in predicting corneal graft rejection.
Viridiana Kocaba +3 more
semanticscholar +1 more source
Killer immunoglobulin-like receptor (KIR) and HLA genotypes affect the outcome of allogeneic kidney transplantation. [PDF]
PLoS ONE, 2012 BACKGROUND: Recipient NK cells may detect the lack of recipient's (i.e., self) HLA antigens on donor renal tissue by means of their killer cell immunoglobulin-like receptors (KIRs).
Izabela Nowak +15 more
doaj +1 more source
ORTHOCLONE OKT3 in treatment of allografts rejected under cyclosporine-steroid therapy [PDF]
, 1986 ORTHOCLONE OKT3 in conjunction with cyclosporine and steroids appears to be an effective immunosuppressive combination in achieving reversal of renal and hepatic rejection.
Fung, JJ, Starzl, TE
core