Body Composition Assessment Provides Prognostic Information in Patients With Cancer Affected by Chronic Graft vs. Host Disease [PDF]
Background Additional tools are needed to assess mortality risk among patients with cancer. Patients with chronic graft vs. host disease (cGVHD) after allogeneic haematopoietic cell transplantation (HCT) represent a high‐risk cancer population with ...
Asmita Mishra+8 more
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Acetabular Insufficiency Fractures in the Setting of Graft vs Host Disease: A Report of Two Cases [PDF]
We report a case series of 2 patients with unilateral acetabular insufficiency fractures who received allogeneic peripheral blood stem cell transplantation for hematologic malignancies complicated by chronic graft vs host disease. These were managed with
Warren Nielsen, BS, Kathryn Schabel, MD
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Acute graft-vs-host disease [PDF]
Acute graft-vs-host disease (GVHD) is a major obstacle to safe allogeneic hematopoietic stem cell transplantation (HSCT), leading to a significant morbidity and mortality. GVHD occurs when transplanted donor T lymphocytes react to foreign host cells. It causes a wide variety of host tissue injuries.
Hakan Göker+2 more
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AAV-mediated expression of HLA-G for the prevention of experimental ocular graft vs. host disease [PDF]
Ocular graft versus host disease (OGvHD) develops after allogeneic hematopoietic stem cell transplantation (HSCT) and manifests as ocular surface inflammatory disease.
Jacob P. Nilles+8 more
doaj +2 more sources
Activated CD4 + T lymphocyte is a potential biomarker for acute graft-vs.-host disease after hematopoietic stem cell transplantation in children with transfusion-dependent β-thalassemia [PDF]
BackgroundAcute graft-vs.-host disease (aGVHD) is still one of the most common and life-threatening complications of allogeneic hematopoietic stem cell transplantation (HSCT).
Ken Huang, Jianming Luo
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Effect of KRN7000 on induced graft-vs-host disease [PDF]
Graft-vs-host disease (GVHD) is a serious complication of allogeneic stem cell transplantation (SCT) and donor lymphocyte infusion (DLI), for which no effective therapy exists. In our study, KRN7000, a synthetic analog of alpha-galactosylceramide, known for its ability to activate natural killer T cells, was tested for its ability to prevent onset of ...
Shoshana Morecki+6 more
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Constrictive Pericarditis Due to Graft-vs-Host Disease [PDF]
A 29-year-old man experienced a diffuse lichenoid rash that extended to his palms (panel A) and soles, peripheral blood eosinophilia, blurry vision, and recalcitrant generalized edema 2 weeks after donor lymphocyte infusion (DLI) for relapsed T-cell acute lymphoblastic leukemia. Skin biopsy revealed vacuolar interface inflammation consistent with graft-
Shernan G. Holtan, Peter C. Spittell
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Xenogeneic humoral Graft-Vs-Host disease following Hamster-to-Rat bone marrow transplantation [PDF]
Toshio Miki+8 more
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We present a case of chronic graft-versus-host disease in a 61-year-old woman with a history of B-cell chronic lymphocytic leukemia that was treated with an allogeneic bone marrow transplant from an unrelated donor. The patient initially presented with erythematous patches on the trunk and extremities that evolved into reticulated, hyperpigmented ...
Tran, Kathleen+3 more
openaire +4 more sources
Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD
Graft-versus-host disease (GVHD) is a life-threatening systemic complication of allogeneic hematopoietic stem cell transplantation (HSCT) characterized by dysregulation of T and B cell activation and function, scleroderma-like features, and multi-organ ...
Deepika Raman+7 more
doaj +1 more source