Constrictive Pericarditis Due to Graft-vs-Host Disease [PDF]
A 29-year-old man experienced a diffuse lichenoid rash that extended to his palms (panel A) and soles, peripheral blood eosinophilia, blurry vision, and recalcitrant generalized edema 2 weeks after donor lymphocyte infusion (DLI) for relapsed T-cell acute lymphoblastic leukemia. Skin biopsy revealed vacuolar interface inflammation consistent with graft-
Shernan G. Holtan, Peter C. Spittell
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Effect of KRN7000 on induced graft-vs-host disease [PDF]
Graft-vs-host disease (GVHD) is a serious complication of allogeneic stem cell transplantation (SCT) and donor lymphocyte infusion (DLI), for which no effective therapy exists. In our study, KRN7000, a synthetic analog of alpha-galactosylceramide, known for its ability to activate natural killer T cells, was tested for its ability to prevent onset of ...
Osnat Eizik+6 more
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Xenogeneic humoral Graft-Vs-Host disease following Hamster-to-Rat bone marrow transplantation [PDF]
Toshio Miki+8 more
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Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study [PDF]
Graft-versus-host disease is the main cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. First-line treatment is based on the use of high doses of corticosteroids.
Grupo Español de Trasplante Hematopoyético (GETH)+2 more
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We present a case of chronic graft-versus-host disease in a 61-year-old woman with a history of B-cell chronic lymphocytic leukemia that was treated with an allogeneic bone marrow transplant from an unrelated donor. The patient initially presented with erythematous patches on the trunk and extremities that evolved into reticulated, hyperpigmented ...
Tran, Kathleen+3 more
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Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD
Graft-versus-host disease (GVHD) is a life-threatening systemic complication of allogeneic hematopoietic stem cell transplantation (HSCT) characterized by dysregulation of T and B cell activation and function, scleroderma-like features, and multi-organ ...
Deepika Raman+7 more
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Small Bowel Perforation Associated With Gastrointestinal Graft-Versus-Host Disease and Cytomegalovirus Enteritis in a Patient With Leukemia: A Case Report With Literature Review [PDF]
Gastrointestinal graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation. Concomitant cytomegalovirus (CMV) enteritis worsens the prognosis of this condition.
Kwang-Seop Song+9 more
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Role of HRCT Chest in Post Stem Cell Transplant Recipients Suspected of Pulmonary Complications [PDF]
Introduction: Stem cell transplantation is today’s procedure of choice for management of various hematopoietic malignant and severe immunogenic disorders. High Resolution Computed Tomography (HRCT) is a common technique for the diagnosis of pulmonary
Abhishek Dwivedi+3 more
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Rehabilitation in Children With Sclerodermoid Chronic Graft-Versus-Host Disease: Case Series [PDF]
Joint contracture in chronic graft-versus-host disease (cGVHD) is refractory to treatment, and tends to deteriorate gradually over time. There is scant clinical research focusing on timing and intensity of rehabilitation on joint contractures in children
Minji Jung, In Young Sung, Eun Jae Ko
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Prevention of graft-vs.-host disease [PDF]
Allogeneic hematopoietic cell transplantation (HCT) is a curative treatment for many malignant and non-malignant hematologic disorders. However, graft-vs.-host disease (GVHD) remains a major complication of allogeneic HCT and limits the success of this approach.This paper reviews recent developments in the prevention of acute and chronic GVHD.
Rainer Storb, Andrew R. Rezvani
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