Results 81 to 90 of about 423,873 (294)

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures [PDF]

, 2017
A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as ...
Cabral, Tània, Franco García, María Lourdes, Lorenzetti, Alice, Marquez, Yolanda, Puiggalí Bellalta, Jordi, Turón Dols, Pau, Valle Mendoza, Luis Javier del   +6 more
core   +2 more sources

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Screening for Antibacterial Activity of Andrographis paniculata Used in Malaysian Folkloric Medicine: A Possible Alternative for the Treatment of Skin Infections [PDF]

, 2010
In this study non-polar (dichloromethane) and polar (MeOH & aqueous) extracts of A. paniculata (whole plant) were evaluated for in vitro antibacterial activity against 12 skin disease causing bacterial strains (7 gram positive strains; Staphylococcus ...
Ahmed, Q. U., Omar, M. N., Samah, O. A., Sule, A.   +3 more
core   +1 more source

Bacterial resistance to antimicrobial agents and its impact on veterinary and human medicine [PDF]

, 2016
Background Antimicrobial resistance has become a major challenge in veterinary medicine, particularly in the context of bacterial pathogens that play a role in both humans and animals.
Aarestrup, Abedon, Arais, Becker, Bikard, Blondeau, Brackman, Bradford, Brandenburg, Brogden, Burrus, Bush, Bush, Bywater, Chopra, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Connell, Couto, Cuny, D'Costa, Damborg, Duijkeren, Ewers, Ewers, Falgenhauer, Feßler, Fischetti, Fuente-Núñez, Giessen, Goh, Grobbel, Grobbel, Groves, Guardabassi, Hall, Harada, Harrison, Hill, Hillier, International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC), Kadlec, Kadlec, Kadlec, Kadlec, Kehrenberg, Köck, Laube, Lefebvre, Lindsay, Lloyd, Long, Lyon, Lüthje, Maaland, Maddox, Magiorakos, Mascaretti, McCarthy, McCarthy, McNulty, Michael, Michael, Michael, Moodley, Mueller, Nienhoff, Nobrega, O'Neill, Paterson, Perreten, Poole, Putman, Ramirez, Redgrave, Richter, Riesenberg, Roberts, Roberts, Roberts, Ruiz, Rule, Schaufler, Schmiedel, Schneider, Schuch, Schultz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Scott, Shen, Sing, Soares, Sobral, Thandar, Thomas, Tsonos, van, von, Walther, Wang, Weiß, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Werckenthin, Westgarth, Westgarth, White, Wu, Zervos, Zhao, Zurek   +123 more
core   +3 more sources

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

Emerging Therapies for Serious Gram-Positive Bacterial Infections: A Focus on Linezolid [PDF]

Clinical Infectious Diseases, 2000
Respiratory tract infections and skin and soft-tissue infections frequently are caused by gram-positive cocci, and treating these infections with standard antibiotics has recently become problematic. Many of the primary pathogens causing these infections are now resistant to current standard treatment regimens.
openaire   +2 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source