Results 21 to 30 of about 4,412,822 (263)

Gram-negative bacteria and their enzyme-producing drug resistance mechanism from BSI suspected patients.

, 2023
Gram-negative bacteria and their enzyme-producing drug resistance mechanism from BSI suspected patients.
Adey Feleke Desta (11979332), Zelalem Desalegn (3140310), Solomon Gizaw Derese (16455660), Tamrat Abebe (59007), Tesfaye Sisay Tessema (6855155), Gurja Belay Woldemichael (16455654), Solomon Gebreselasie (4392502), Tizazu Zenebe Zelelie (16455663), Daniel Beshah (16455651), Esmael Besufikad Belachew (16455657)   +9 more
core   +1 more source

Approaches forPurifying Recombinant Proteins from Gram Negative Bacteria [PDF]

, 2019
The ideal vaccine can generate a strong immune reaction without adverse effects on the body. Thus, many vaccines are now created using recombinant technology to accomplish this goal. Purification of recombinant proteins produced in Gram negative bacteria
Burran, Susan
core   +1 more source

Development of an NGS-Based Workflow for Improved Monitoring of Circulating Plasmids in Support of Risk Assessment of Antimicrobial Resistance Gene Dissemination

Antibiotics, 2020
Antimicrobial resistance (AMR) is one of the most prominent public health threats. AMR genes localized on plasmids can be easily transferred between bacterial isolates by horizontal gene transfer, thereby contributing to the spread of AMR.
Bas Berbers, Pieter-Jan Ceyssens, Pierre Bogaerts, Kevin Vanneste, Nancy H. C. Roosens, Kathleen Marchal, Sigrid C. J. De Keersmaecker   +6 more
doaj   +1 more source

In host evolution of beta lactam resistance during active treatment for Pseudomonas aeruginosa bacteremia

Frontiers in Cellular and Infection Microbiology, 2023
Multidrug-resistant (MDR) Pseudomonas aeruginosa has been declared a serious threat by the United States Centers for Disease Control and Prevention. Here, we used whole genome sequencing (WGS) to investigate recurrent P. aeruginosa bloodstream infections
Natasha Spottiswoode, Samantha Hao, Samantha Hao, Estella Sanchez-Guerrero, Angela M. Detweiler, Honey Mekonen, Norma Neff, Henriette Macmillan, Brian S. Schwartz, Joanne Engel, Joseph L. DeRisi, Joseph L. DeRisi, Steven A. Miller, Steven A. Miller, Charles R. Langelier, Charles R. Langelier   +15 more
doaj   +1 more source

Gram-Negative Bacterial Lysins

Antibiotics, 2020
Antibiotics have had a profound impact on human society by enabling the eradication of otherwise deadly infections. Unfortunately, antibiotic use and overuse has led to the rapid spread of acquired antibiotic resistance, creating a major threat to public
Chandrabali Ghose, Chad W. Euler
doaj   +1 more source

Molecular surveillance of carbapenemase-producing Pseudomonas aeruginosa at three medical centres in Cologne, Germany

Antimicrobial Resistance and Infection Control, 2019
Background Pseudomonas aeruginosa is a common pathogen causing hospital-acquired infections. Carbapenem resistance in P. aeruginosa is either mediated via a combination of efflux pumps, AmpC overexpression, and porin loss, or through an acquired ...
Elena Schäfer, Monika Malecki, Carlos J. Tellez-Castillo, Niels Pfennigwerth, Lennart Marlinghaus, Paul G. Higgins, Frauke Mattner, Andreas F. Wendel   +7 more
doaj   +1 more source

Comparison of testing methods assessing the in vitro efficacy of the combination of aztreonam with avibactam on multidrug-resistant Gram-negative bacilli

Annals of Clinical Microbiology and Antimicrobials
Background Aztreonam-avibactam (ATM-AVI) combination shows promising effectiveness on most carbapenemase-producing Gram-negatives, yet standardized antibiotic susceptibility testing (AST) methods for evaluating the combination in clinical laboratories is
Corentin Deckers, Florian Bélik, Olivier Denis, Pierre Bogaerts, Isabel Montesinos, Catherine Berhin, Warda Bouchahrouf, Martin Hoebeke, Stephanie Evrard, Nicolas Gilliard, Merve Okur, Te-Din Huang   +11 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source