Results 151 to 160 of about 113,801 (204)
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Journal of Pharmaceutical Sciences, 1968
Griseofulvin, in fine and coarse grades, has been bowl granulated using binder solutions. The granules have been assessed for strength and flow characteristics. A mechanism of granule growth has been suggested, which satisfactorily explains the experimental results.
C F, Harwood, N, Pilpel
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Griseofulvin, in fine and coarse grades, has been bowl granulated using binder solutions. The granules have been assessed for strength and flow characteristics. A mechanism of granule growth has been suggested, which satisfactorily explains the experimental results.
C F, Harwood, N, Pilpel
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Experientia, 1984
Although considerable knowledge has been acquired concerning the chemical nature of insulin and its pathway of biosynthesis, relatively little is known about the other proteins which constitute the insulin secretory granule. This, in part, has been a consequence of the difficulties of working with pancreatic islets as a tissue source and the attendant ...
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Although considerable knowledge has been acquired concerning the chemical nature of insulin and its pathway of biosynthesis, relatively little is known about the other proteins which constitute the insulin secretory granule. This, in part, has been a consequence of the difficulties of working with pancreatic islets as a tissue source and the attendant ...
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Quantification and granulation
2001 IEEE International Conference on Systems, Man and Cybernetics. e-Systems and e-Man for Cybernetics in Cyberspace (Cat.No.01CH37236), 2002Data mining holds the promise of extracting unsuspected information from very large databases: Methods have been developed to build association rules from categorical data. However, often many fine grained rules are generated. Additionally, much real data is not only categorical; it is quantitative. In forming association rules, quantitative values are
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Coupling granule properties and granulation rates in high-shear granulation
Powder Technology, 2003It is possible to link granulation rates to granule properties. The linkage is by multiple dimension population balance equations that, by means of simplifying assumptions, can be reduced to multiple one-dimensional (1-D) population balance equations (PBES).
Biggs, CA +7 more
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Intelligent granules: Are eosinophil crystalloid granules inimitable?
Journal of Allergy and Clinical Immunology, 2010The controversy surrounding the effector function of eosinophils in health and disease continues at both the clinical and basic discovery levels. Two recent studies reported that an anti-human IL-5 mAb (mepolizumab) specifically targeting eosinophils significantly reduced asthma exacerbations, providing interesting insights into the potential role of ...
Salahaddin, Mahmudi-Azer +2 more
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Microbial communities of aerobic granules: Granulation mechanisms
Bioresource Technology, 2014Aerobic granulation is an advanced biological wastewater treatment technology. This study for the first time identified the microbial communities of sliced samples of mature granules by polymerase chain reaction (PCR) amplification and denaturing gradient gel electrophoresis (DGGE) technique and those of whole growing granules by high-throughput ...
Yi, Lv +4 more
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Granulation of Acetaminophen by a Rotating Fluidized-Bed Granulator
Pharmaceutical Development and Technology, 2000The purpose of this research was to evaluate the use of a rotating fluidized-bed granulator to produce acetaminophen granules with sufficient binding force between particles and good plasticity in tablets. Ethenzamide and ascorbic acid were used to compare the relationship between granulation and the sample wetness.
T, Kawaguchi +9 more
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Effect of the Granulation Process on Nitrofurantoin Granule Characteristics
Drug Development and Industrial Pharmacy, 1998We studied four granulation methods on the same quantitative and qualitative formula: wet massing by forced agglomeration (Lödige) and free agglomeration (Glatt); and dry massing by slugging and roller compaction technique. Three different particle sizes of nitrofurantoin (bioinequivalent drug) were used. The nitrofurantoin particle size has a very low
P, Arnaud, D, Brossard, J C, Chaumeil
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Coalescence of deformable granules in wet granulation processes
AIChE Journal, 2000Abstract In this work, the coalescence of deformable granules in wet granulation processes is modelled. The model accounts for both the mechanical properties of the granules and the effect of the liquid layer at the granule surface. It is an extension to the model of Ennis et al.
Liu, L. X. +3 more
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Effects of High-Shear Granulation on Granulate Homogeneity
Pharmaceutical Development and Technology, 1999This study considers the effects of particle size of the powder constituents, and of impeller speed on the homogeneity of drug distribution on granulations produced in high-speed mixers. When a micronized low-dose steroid hormone was granulated together with unmicronized lactose in a Vactron 75 high-shear granulator at 250 rpm, strong inhomogeneities ...
H, Vromans +2 more
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