Results 161 to 170 of about 113,801 (204)
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Twin screw granulation: Steps in granule growth
International Journal of Pharmaceutics, 2012The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of granulation liquid on properties of granules was studied.
Ranjit M, Dhenge +3 more
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Roles of Granule Size in Over-Granulation During High Shear Wet Granulation
Journal of Pharmaceutical Sciences, 2010A mechanistic understanding of the over-granulation problem during high shear wet granulation (HSWG) process can guide efficient development of robust formulation and manufacturing process. Using microcrystalline cellulose (MCC) as a model compound, we demonstrate that size enlargement is an important mechanism for over-granulation in HSWG.
Limin, Shi +2 more
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Pharmaceutical Research, 2005
To investigate the background of the observed relationship between measured torque and granule size in high-shear granulation processes.Torque was measured during the granulation process; the behavior of individual wet granules during compaction was investigated using micromanipulation.
Bouwman, A.M. +6 more
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To investigate the background of the observed relationship between measured torque and granule size in high-shear granulation processes.Torque was measured during the granulation process; the behavior of individual wet granules during compaction was investigated using micromanipulation.
Bouwman, A.M. +6 more
openaire +3 more sources
A study on the preparation of granules by mixer granulation
Archives of Pharmacal Research, 1979A first systematic approach on new and simple preparation method of spherical granules in the system using organic granulating solution was carried out. Mixer granulation required narrow range of moisture content but gentle action of tumbling in the mixer and capillary forces were adequate to compact the porous mass and also were highly effective to ...
Kang Choon Lee +3 more
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1999
In multi-resolution data handling, a less detailed structure is often derived from a more detailed one by amalgamating elements which are indistinguishable at the lower level of detail. This gathering together of indistinguishable elements is called a granulation of the more detailed structure. When handling spatial data at several levels of detail the
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In multi-resolution data handling, a less detailed structure is often derived from a more detailed one by amalgamating elements which are indistinguishable at the lower level of detail. This gathering together of indistinguishable elements is called a granulation of the more detailed structure. When handling spatial data at several levels of detail the
openaire +1 more source
Alternative Granulation Technique: Melt Granulation
Drug Development and Industrial Pharmacy, 1996AbstractA melt granulation process has been investigated (1, 2) which efficiently agglomerates pharmaceutical powders for use in both immediate- and sustained-release solid dosage forms. The process utilizes materials that are effective as granulating fluids when they are in the molten state.
Alan Royce +3 more
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Siderotic Granules and the Granules of Punctate Basophilia
British Journal of Haematology, 1963openaire +2 more sources