Results 91 to 100 of about 5,501,717 (307)
Denervation-induced homeostatic dendritic plasticity in morphological granule cell models
Neuronal death and subsequent denervation of target areas are major consequences of several neurological conditions such asischemia or neurodegeneration (Alzheimer's disease). The denervation-induced axonal loss results in reorganization of the dendritic
Hermann Cuntz +2 more
doaj +1 more source
Fate of Shed Mast Cell Granules.
SummaryIt has been observed that following mild trauma to the skin of mice, degranulation of mast cells occurs in the subcutaneous connective tissue and is followed by the appearance of metachromatic granules within the cytoplasm of surrounding fibroblasts. Investigation of this phenomenon by subcutaneous injection of isolated mast cell granules showed
R D, HIGGINBOTHAM +2 more
openaire +2 more sources
Bioinspired Bouligand architectures are translated into biodegradable polymer laminates with integrated sensing, revealing how structural design governs multifunctional performance. A 20° interlayer rotation optimizes strength, flexibility, and electromechanical response, while embedded nanotube networks enable real‐time damage detection and wearable ...
Piotr K. Szewczyk +4 more
wiley +1 more source
Regulation of output spike patterns by phasic inhibition in cerebellar granule cells
The complex interplay of multiple molecular mechanisms taking part to synaptic integration is hard to disentangle experimentally. Therefore, we developed a biologically realistic computational model based on the rich set of data characterizing the ...
Thierry Ralph Nieus +4 more
doaj +1 more source
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye +11 more
wiley +1 more source
Enriched Environment Shortens the Duration of Action Potentials in Cerebellar Granule Cells
Environmental enrichment for rodents is known to enhance motor performance. Structural and molecular changes have been reported to be coupled with an enriched environment, but functional alterations of single neurons remain elusive.
Abdelmoneim Eshra +2 more
doaj +1 more source
Despite a wealth of in vitro and modelling studies it remains unclear how neuronal populations in the cerebellum interact in vivo. We address the issue of how the cerebellar input layer processes sensory information, with particular focus on the granule ...
Holtzman, T. +14 more
core +1 more source
Interface Dynamics in Biomolecular Condensates by High‐Speed AFM
High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria +6 more
wiley +1 more source
Dentate granule cells process information from the enthorinal cortex en route to the hippocampus proper. These neurons have a very negative resting membrane potential and are relatively silent in the slice preparation.
Arnaud J Ruiz, Dimitri M Kullmann
doaj +1 more source

