Results 91 to 100 of about 5,501,717 (307)

Denervation-induced homeostatic dendritic plasticity in morphological granule cell models

open access: yesFrontiers in Systems Neuroscience, 2014
Neuronal death and subsequent denervation of target areas are major consequences of several neurological conditions such asischemia or neurodegeneration (Alzheimer's disease). The denervation-induced axonal loss results in reorganization of the dendritic
Hermann Cuntz   +2 more
doaj   +1 more source

Fate of Shed Mast Cell Granules.

open access: yesExperimental Biology and Medicine, 1956
SummaryIt has been observed that following mild trauma to the skin of mice, degranulation of mast cells occurs in the subcutaneous connective tissue and is followed by the appearance of metachromatic granules within the cytoplasm of surrounding fibroblasts. Investigation of this phenomenon by subcutaneous injection of isolated mast cell granules showed
R D, HIGGINBOTHAM   +2 more
openaire   +2 more sources

Architectural Tuning of Bouligand Electrospun Laminates Enables Coupled Mechanical Robustness and Electromechanical Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Bioinspired Bouligand architectures are translated into biodegradable polymer laminates with integrated sensing, revealing how structural design governs multifunctional performance. A 20° interlayer rotation optimizes strength, flexibility, and electromechanical response, while embedded nanotube networks enable real‐time damage detection and wearable ...
Piotr K. Szewczyk   +4 more
wiley   +1 more source

Regulation of output spike patterns by phasic inhibition in cerebellar granule cells

open access: yesFrontiers in Cellular Neuroscience, 2014
The complex interplay of multiple molecular mechanisms taking part to synaptic integration is hard to disentangle experimentally. Therefore, we developed a biologically realistic computational model based on the rich set of data characterizing the ...
Thierry Ralph Nieus   +4 more
doaj   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

open access: yesAdvanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye   +11 more
wiley   +1 more source

Enriched Environment Shortens the Duration of Action Potentials in Cerebellar Granule Cells

open access: yesFrontiers in Cellular Neuroscience, 2019
Environmental enrichment for rodents is known to enhance motor performance. Structural and molecular changes have been reported to be coupled with an enriched environment, but functional alterations of single neurons remain elusive.
Abdelmoneim Eshra   +2 more
doaj   +1 more source

Multiple extra-synaptic spillover mechanisms regulate prolonged activity in cerebellar Golgi cell - granule cell loops

open access: yes, 2011
Despite a wealth of in vitro and modelling studies it remains unclear how neuronal populations in the cerebellum interact in vivo. We address the issue of how the cerebellar input layer processes sensory information, with particular focus on the granule ...
Holtzman, T.   +14 more
core   +1 more source

Interface Dynamics in Biomolecular Condensates by High‐Speed AFM

open access: yesAdvanced Materials Interfaces, EarlyView.
High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria   +6 more
wiley   +1 more source

Ionotropic receptors at hippocampal mossy fibres: roles in axonal excitability, synaptic transmission and plasticity

open access: yesFrontiers in Neural Circuits, 2013
Dentate granule cells process information from the enthorinal cortex en route to the hippocampus proper. These neurons have a very negative resting membrane potential and are relatively silent in the slice preparation.
Arnaud J Ruiz, Dimitri M Kullmann
doaj   +1 more source

J Neurophysiol 90: 2478–2483, 2003; 10.1152/jn.00399.2003. NO Enhances Presynaptic Currents During Cerebellar Mossy Fiber—

open access: yes, 2003
currents during cerebellar mossy fiber: granule cell LTP.
Granule Cell Ltp   +5 more
core  

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