Results 81 to 90 of about 178,493 (310)

Investigating the interplay between excitatory neurotransmission and GABAa receptor expression and trafficking in the stargazer mutant mouse [PDF]

, 2006
The stargazer mutant mouse is an animal model of human absence epilepsy and cerebellar ataxia. The stargazer mutation results in the complete ablation of expression of TARPy2， an AMPA receptor (AMPAR) auxiliary subunit.
Payne, Helen Louise
core  

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Lateral signal spread is dependent on the mitral-granule-mitral pathway.

, 2016
(A) Schematic of the MOB circuitry with EPL surgical microcut, and preservation of the interglomerular-interneuron pathway (red highlights). ONL, olfactory nerve layer; GL, glomerular layer; EPL, external plexiform layer; MCL, mitral cell layer; IPL ...
Cedric R. Uytingco (3371243), Adam C. Puche (266747), Steven D. Munger (266748)   +2 more
core   +1 more source

Purkinje cell responses during diverse Granule cell plasticity scenarios

, 2022
Purkinje cell responses during diverse Granule cell plasticity ...
Robin De Schepper
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Cerebellar granule cells transplanted in vivo can follow physiological and unusual migratory routes to integrate into the recipient cortex

Neurobiology of Disease, 2008
CNS repair by cell transplantation requires new neurons to integrate into complex recipient networks. We assessed how the migratory route of transplanted granule neurons and the developmental stage of the host rat cerebellum influence engraftment.
Ian Martin Williams, Barbara Carletti, Ketty Leto, Lorenzo Magrassi, Ferdinando Rossi   +4 more
doaj   +1 more source

Gradients in the mammalian cerebellar cortex enable Fourier-like transformation and improve storing capacity

eLife, 2020
Cerebellar granule cells (GCs) make up the majority of all neurons in the vertebrate brain, but heterogeneities among GCs and potential functional consequences are poorly understood.
Isabelle Straub, Laurens Witter, Abdelmoneim Eshra, Miriam Hoidis, Niklas Byczkowicz, Sebastian Maas, Igor Delvendahl, Kevin Dorgans, Elise Savier, Ingo Bechmann, Martin Krueger, Philippe Isope, Stefan Hallermann   +12 more
doaj   +1 more source

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source

A novel G3BP1-GFP reporter human lung cell system enabling real-time monitoring of stress granule dynamics for in vitro lung toxicity assessment

Ecotoxicology and Environmental Safety
Under various cellular stress conditions, including exposure to toxic chemicals, RNA-binding proteins (RBPs), including Ras GTPase-activating protein-binding protein 1 (G3BP1), aggregate and form stress granule complexes, which serve as hallmarks of ...
Sangsoo Lee, Seung-Yeon Kim, Eunhye Kwon, Sunkyung Choi, Da-Min Jung, Kee K. Kim, Eun-Mi Kim   +6 more
doaj   +1 more source