Results 61 to 70 of about 178,493 (310)

Cell-autonomous Cbln1 is required for cerebellar granule cell axon growth.

, 2022
(A) In situ hybridization of Cbln1 in cerebella during P4 and P8. Cbln1 mRNA is specifically and highly expressed in granule cells, esp. in the IGL. Scale bars, 500 μm.
Peng Han (623382), Yuanchu She (14134787), Qingjun Wang (1793110), Sheng-Jian Ji (14134802), Samie R. Jaffrey (1306116), Zhuoxuan Yang (14134790), Xiaopeng Luo (14134796), Mengru Zhuang (14134793), Junda Zhu (7991426), Chaoqun Yin (14134799)   +9 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Structured sampling of molecularly classified mossy fiber inputs by cerebellar granule cells

Frontiers in Computational Neuroscience
The cerebellar granule cell layer receives mossy fiber inputs from diverse brain regions, yet the principles governing how individual granule cells sample distinct types of inputs remain poorly understood. Using a volumetric correlated light and electron
Xiaomeng Han, Elif Sevde Meral, Jeff W. Lichtman   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Camillo Golgi on Cerebellar Granule Cells [PDF]

The Cerebellum, 2012
info:eu-repo/semantics ...
Mazzarello, Paolo, Haines, Duane, Manto, Mario   +2 more
openaire   +3 more sources

Perisomatic innervation on the semilunar granule cells and outer molecular layer granule cells of the dentate gyrus of the mouse

Frontiers in Neuroanatomy
Semilunar granule cells in the dentate gyrus represent a distinct type of granule cell, distinguished by their unique morphology and physiology. These cells are located within the inner molecular layer and the upper juxta-granule cell layer of the ...
Laura Rovira-Esteban, Isaac Vieco-Martí, Javier Herraiz-Cabanes, Emilio Varea, Juan Nacher, Juan Nacher, Juan Nacher, Carlos Crespo, José Miguel Blasco-Ibáñez   +8 more
doaj   +1 more source

Regulation of cerebellar network development by granule cells and their molecules

Frontiers in Molecular Neuroscience, 2023
The well-organized cerebellar structures and neuronal networks are likely crucial for their functions in motor coordination, motor learning, cognition, and emotion.
Muwoong Kim, Muwoong Kim, Soyoung Jun, Soyoung Jun, Heeyoun Park, Keiko Tanaka-Yamamoto, Keiko Tanaka-Yamamoto, Yukio Yamamoto   +7 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation

Journal of Neuroinflammation, 2011
Background Although the cellular mechanisms responsible for the pathogenesis of autism are not understood, a growing number of studies have suggested that localized inflammation of the central nervous system (CNS) may contribute to the development of ...
Dobkin Carl, Malik Mazhar, Sheikh Ashfaq M, Zou Hua, Wei Hongen, Brown W Ted, Li Xiaohong   +6 more
doaj   +1 more source

Cerebellar Patterning Defects in Mutant Mice

Frontiers in Neuroscience, 2021
The cerebellar cortex is highly compartmentalized and serves as a remarkable model for pattern formation throughout the brain. In brief, the adult cerebellar cortex is subdivided into five anteroposterior units—transverse zones—and subsequently, each ...
Richard Hawkes
doaj   +1 more source