Results 41 to 50 of about 178,493 (310)

Cerebellar granule cells are predominantly generated by terminal symmetric divisions of granule cell precursors [PDF]

Developmental Dynamics, 2015
Background: Neurons in the central nervous system (CNS) are generated by symmetric and asymmetric cell division of neural stem cells and their derivative progenitor cells. Cerebellar granule cells are the most abundant neurons in the CNS, and are generated by intensive cell division of granule cell precursors (GCPs) during postnatal development ...
Kie, Nakashima, Hiroki, Umeshima, Mineko, Kengaku   +2 more
openaire   +2 more sources

Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures

, 2012
During postnatal development hippocampal dentate granule cells (GCs) often extend dendrites from the basal pole of their cell bodies into the hilar region. These so-called hilar basal dendrites (hBD) usually regress with maturation.
Gerlind Schuldt, Zahn, Nadine, Maggio, Nicola, Willems, Laurent Maximilian, Nicola Maggio, Thomas Deller, Vnenčák, Matej, Denise Becker, Jedlička, Peter, Matej Vnencak, Schuldt, Gerlind, Nadine Zahn, Vlachos, Andreas, Peter Jedlicka, Andreas Vlachos, Becker, Denise, Deller, Thomas, Laurent Maximilian Willems   +17 more
core   +1 more source

Effects of Allogeneic Bone Substitute Configurations on Cell Adhesion Process In Vitro

Orthopaedic Surgery, 2023
Objective To explore the potential effect of three allogenic bone substitute configurations on the viability, adhesion, and spreading of osteoblasts in vitro.
Jie Liu, Li Yang, Hao Zhang, Jing‐yu Zhang, Yong‐cheng Hu   +4 more
doaj   +1 more source

Labeling of Precursor Granule Cells in the Cerebellum by ex vivo Electroporation

Bio-Protocol, 2013
This protocol will be useful to introduce the genes of interest into the cerebellar granule cells at early stages of development. Since the granule cell precursors are localized in the external granule layer before migration, DNA plasmids can be ...
Aya Ito-Ishida
doaj   +1 more source

Differential Structural Development of Adult-Born Septal Hippocampal Granule Cells in the Thy1-GFP Mouse, Nuclear Size as a New Index of Maturation. [PDF]

PLoS ONE, 2015
Adult neurogenesis is frequently studied in the mouse hippocampus. We examined the morphological development of adult-born, immature granule cells in the suprapyramidal blade of the septal dentate gyrus over the period of 7-77 days after mitosis with ...
Tijana Radic, Omar Al-Qaisi, Tassilo Jungenitz, Marcel Beining, Stephan W Schwarzacher   +4 more
doaj   +1 more source

Entorhinal denervation induces homeostatic synaptic scaling of excitatory postsynapses of dentate granule cells in mouse organotypic slice cultures

, 2012
Denervation-induced changes in excitatory synaptic strength were studied following entorhinal deafferentation of hippocampal granule cells in mature (≥3 weeks old) mouse organotypic entorhino-hippocampal slice cultures.
Roeper, Jochen, Roeper Jochen, Winkels, Raphael, Denise Becker (179935), Thomas Deller, Thomas Deller (179947), Denise Becker, Jedlička, Peter, Becker Denise, Jochen Roeper, Jedlicka Peter, Winkels Raphael, Andreas Vlachos (47497), Vlachos Andreas, Vlachos, Andreas, Andreas Vlachos, Peter Jedlicka, Jochen Roeper (179944), Becker, Denise, Peter Jedlicka (179938), Raphael Winkels (179941), Deller Thomas, Deller, Thomas, Raphael Winkels   +23 more
core   +1 more source

Effects of Phosphatidylserine Source of Docosahexaenoic Acid on Cerebellar Development in Preterm Pigs

Brain Sciences, 2020
Preterm birth, a major contributor to infant mortality and morbidity, impairs development of the cerebellum, the brain region involved in cognitive processing and motor function.
Daniel Chizhikov, Randal K. Buddington, Igor Y. Iskusnykh   +2 more
doaj   +1 more source

mGluR2 Postsynaptically Senses Granule Cell Inputs at Golgi Cell Synapses

, 2003
In the cerebellar circuit, Golgi cells are thought to contribute to information processing and integration via feedback mechanisms. In these mechanisms, dynamic modulation of Golgi cell excitability is necessary because GABA from Golgi cells causes tonic
Watanabe, Dai, Nakanishi, Shigetada
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Rab3D is critical for secretory granule maturation in PC12 cells.

, 2013
Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex.
Sharon A. Tooze (391543), Kögel Tanja, Copier, J., Hodneland, E, Gerdes, HH, Gerdes Hans-Hermann, Tooze, S. A., Tooze Sharon A., Copier, J, Rüdiger Rudolf (151449), Tanja Kögel, Romano Regazzi, Rudolf Rüdiger, Copier John, Gerdes, H. H., Tooze, SA, Tanja Kögel (391540), Kögel, T., Hans-Hermann Gerdes, Kögel, T, Hodneland Erlend, John Copier, Tooze, S.A., Rudolf, R., Regazzi Romano, Regazzi, R, Erlend Hodneland, Gerdes, H.H., Erlend Hodneland (391541), Regazzi, R., Sharon A Tooze, Hodneland, E., John Copier (391542), Rudolf, R, Romano Regazzi (210061), Rüdiger Rudolf, Hans-Hermann Gerdes (127873)   +36 more
core   +1 more source