Results 31 to 40 of about 5,501,717 (307)

Long-Term Effects of Moderate Concussive Brain Injury During Adolescence on Synaptic and Tonic GABA Currents in Dentate Granule Cells and Semilunar Granule Cells

open access: yesFrontiers in Neuroscience, 2022
Progressive physiological changes in the hippocampal dentate gyrus circuits following traumatic brain injury (TBI) contribute to temporal evolution of neurological sequelae.
Akshay Gupta   +7 more
doaj   +1 more source

The distribution of N-acetylgalactosamine in the cochlear nucleus of the gerbil revealed by lectin binding with soybean agglutinin [PDF]

open access: yes, 1994
A horseradish peroxidase conjugated lectin from Glycine max (soy bean agglutinin; SBA) was used to characterise the distribution of N-acetylgalactosamine in the cochlear nucleus of the mongolian gerbil. SBA bound differentially to a variety of structures
Gleich, Otto, Otto Gleich
core   +1 more source

Granule-Dependent NK Cell Killing of Cryptococcus Requires Kinesin to Reposition the Cytolytic Machinery for Directed Cytotoxicity

open access: yesCell Reports, 2018
Summary: Cryptococcus is the most important cause of fungal meningitis in immunocompromised individuals. Host defense against Cryptococcus involves direct killing by NK cells.
Henry Ogbomo   +10 more
doaj   +1 more source

Cadherin-2 controls directional chain migration of cerebellar granule neurons.

open access: yesPLoS Biology, 2009
Long distance migration of differentiating granule cells from the cerebellar upper rhombic lip has been reported in many vertebrates. However, the knowledge about the subcellular dynamics and molecular mechanisms regulating directional neuronal migration
Sandra Rieger   +3 more
doaj   +1 more source

Cerebellar granule cells are predominantly generated by terminal symmetric divisions of granule cell precursors [PDF]

open access: yesDevelopmental Dynamics, 2015
Background: Neurons in the central nervous system (CNS) are generated by symmetric and asymmetric cell division of neural stem cells and their derivative progenitor cells. Cerebellar granule cells are the most abundant neurons in the CNS, and are generated by intensive cell division of granule cell precursors (GCPs) during postnatal development ...
Kie, Nakashima   +2 more
openaire   +2 more sources

Effects of Allogeneic Bone Substitute Configurations on Cell Adhesion Process In Vitro

open access: yesOrthopaedic Surgery, 2023
Objective To explore the potential effect of three allogenic bone substitute configurations on the viability, adhesion, and spreading of osteoblasts in vitro.
Jie Liu   +4 more
doaj   +1 more source

Labeling of Precursor Granule Cells in the Cerebellum by ex vivo Electroporation

open access: yesBio-Protocol, 2013
This protocol will be useful to introduce the genes of interest into the cerebellar granule cells at early stages of development. Since the granule cell precursors are localized in the external granule layer before migration, DNA plasmids can be ...
Aya Ito-Ishida
doaj   +1 more source

Differential Structural Development of Adult-Born Septal Hippocampal Granule Cells in the Thy1-GFP Mouse, Nuclear Size as a New Index of Maturation. [PDF]

open access: yesPLoS ONE, 2015
Adult neurogenesis is frequently studied in the mouse hippocampus. We examined the morphological development of adult-born, immature granule cells in the suprapyramidal blade of the septal dentate gyrus over the period of 7-77 days after mitosis with ...
Tijana Radic   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Effects of Phosphatidylserine Source of Docosahexaenoic Acid on Cerebellar Development in Preterm Pigs

open access: yesBrain Sciences, 2020
Preterm birth, a major contributor to infant mortality and morbidity, impairs development of the cerebellum, the brain region involved in cognitive processing and motor function.
Daniel Chizhikov   +2 more
doaj   +1 more source

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