Results 31 to 40 of about 178,493 (310)

Short-Term Plasticity in Cortical GABAergic Synapses on Olfactory Bulb Granule Cells Is Modulated by Endocannabinoids

Frontiers in Cellular Neuroscience, 2021
Olfactory bulb and higher processing areas are synaptically interconnected, providing rapid regulation of olfactory bulb circuit dynamics and sensory processing. Short-term plasticity changes at any of these synapses could modulate sensory processing and
Fu-Wen Zhou, Adam C. Puche
doaj   +1 more source

Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus

Molecular Brain, 2010
New granule cells are continuously generated in the dentate gyrus of the adult hippocampus. During granule cell maturation, the mechanisms that differentiate new cells not only describe the degree of cell differentiation, but also crucially regulate the ...
Ohira, Koji, Hagihara, Hideo, Toyama, Keiko, Takao Keizo, Kanai Masaaki, Funakoshi Hiroshi, Nakamura Toshikazu, Miyakawa Tsuyoshi   +7 more
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Enzymes of the Mast Cell Granule

Journal of Investigative Dermatology, 1980
Rat mast cell granules contain a spectrum of enzymes as established by histochemical techniques and subcellular fractionation. However, 35% of the beta-glucuronidase, 30% of the beta-D-galactosidase, 14% of the beta-hexosaminidase and all of the acid phosphatase is not available for immunologic release from purified rat serosal mast cells, suggesting ...
Schwartz, Lawrence B., Frank Austen, K.
openaire   +2 more sources

Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input

Frontiers in Integrative Neuroscience, 2014
Golgi cells (GoCs) are specialized interneurons that provide inhibitory input to granule cells in the cerebellar cortex. GoCs are pacemaker neurons that spontaneously fire action potentials, triggering spontaneous inhibitory postsynaptic currents in ...
Paolo eBotta, Aya eZucca, Carlos Fernando Valenzuela   +2 more
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Plasticity in mammalian somatosensory cerebellar maps [PDF]

, 1996
The organization of sensory maps in mammalian brains can change following peripheral injury or experience. Such plasticity has been demonstrated for somatotopic somatosensory maps in various cortical and subcortical areas. In contrast to somatotopic maps,
Morissette, Josee
core   +1 more source

APP Expression in Primary Neuronal Cell Cultures fromP6 Mice during in vitro Differentiation [PDF]

, 1993
Primary neuronal cell cultures from P6 mice were investigated in order to study amyloid protein precursor (APP) gene expression in differentiating neurons.
Sandbrink, R., Masters, C. L., Beyreuther, K., König, G., Mönning, U., Dichgans, Martin   +5 more
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Long-Term Effects of Moderate Concussive Brain Injury During Adolescence on Synaptic and Tonic GABA Currents in Dentate Granule Cells and Semilunar Granule Cells

Frontiers in Neuroscience, 2022
Progressive physiological changes in the hippocampal dentate gyrus circuits following traumatic brain injury (TBI) contribute to temporal evolution of neurological sequelae.
Akshay Gupta, Akshay Gupta, Laura Dovek, Archana Proddutur, Archana Proddutur, Fatima S. Elgammal, Vijayalakshmi Santhakumar, Vijayalakshmi Santhakumar   +7 more
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The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

, 2020
Immune-modulating therapies have revolutionized the treatment of chronic diseases, particularly cancer. However, their success is restricted and there is a need to identify new therapeutic targets. Here, we show that natural killer cell granule protein 7
McEnroe, Benjamin A, Chauhan, Shashi Bhushan, Frame, Teija CM, Ng, Susanna S, Li, Xian-Yang, Wang, Yulin, Corvino, Dillon, Hou, Jiajie, Das, Indrajit, Kuns, Rachel, Yan, Juming, Engwerda, Christian R, De Labastida Rivera, Fabian, Zhang, Ping, et al.   +14 more
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Granule-Dependent NK Cell Killing of Cryptococcus Requires Kinesin to Reposition the Cytolytic Machinery for Directed Cytotoxicity

Cell Reports, 2018
Summary: Cryptococcus is the most important cause of fungal meningitis in immunocompromised individuals. Host defense against Cryptococcus involves direct killing by NK cells.
Henry Ogbomo, Martina Timm-McCann, Tavish Barnes, Richard F. Xiang, Khusraw Jamil, Anutosh Ganguly, Danuta Stack, Shaunna M. Huston, Shu Shun Li, Pina Colarusso, Christopher H. Mody   +10 more
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Cadherin-2 controls directional chain migration of cerebellar granule neurons.

PLoS Biology, 2009
Long distance migration of differentiating granule cells from the cerebellar upper rhombic lip has been reported in many vertebrates. However, the knowledge about the subcellular dynamics and molecular mechanisms regulating directional neuronal migration
Sandra Rieger, Niklas Senghaas, Axel Walch, Reinhard W Köster   +3 more
doaj   +1 more source