Cadherin-2 controls directional chain migration of cerebellar granule neurons.
PLoS Biology, 2009 Long distance migration of differentiating granule cells from the cerebellar upper rhombic lip has been reported in many vertebrates. However, the knowledge about the subcellular dynamics and molecular mechanisms regulating directional neuronal migration
Sandra Rieger +3 more
doaj +1 more source
Cell Reports, 2018 Summary: Cryptococcus is the most important cause of fungal meningitis in immunocompromised individuals. Host defense against Cryptococcus involves direct killing by NK cells.
Henry Ogbomo +10 more
doaj +1 more source
Dynamin Is Functionally Coupled to Insulin Granule Exocytosis [PDF]
, 2007 The insulin granule integral membrane protein marker phogrin-green fluorescent protein was co-localized with insulin in Min6B1 beta-cell secretory granules but did not undergo plasma membrane translocation following glucose stimulation.
Gaisano, HY +7 more
core +2 more sources
Effects of Allogeneic Bone Substitute Configurations on Cell Adhesion Process In Vitro
Orthopaedic Surgery, 2023 Objective To explore the potential effect of three allogenic bone substitute configurations on the viability, adhesion, and spreading of osteoblasts in vitro.
Jie Liu +4 more
doaj +1 more source
Interaction between Granulation and Small-Scale Magnetic Flux Observed by Hinode
, 2009 We study the relationship between granular development and magnetic field evolution in the quiet Sun. 6 typical cases are displayed to exhibit interaction between granules and magnetic elements, and we have obtained the following results.
Bray +19 more
core +2 more sources
Population-scale organization of cerebellar granule neuron signaling during a visuomotor behavior. [PDF]
, 2017 Granule cells at the input layer of the cerebellum comprise over half the neurons in the human brain and are thought to be critical for learning. However, little is known about granule neuron signaling at the population scale during behavior.
Aksay, Emre RF +5 more
core +2 more sources
Cerebellar granule cells are predominantly generated by terminal symmetric divisions of granule cell precursors [PDF]
Developmental Dynamics, 2015 Background: Neurons in the central nervous system (CNS) are generated by symmetric and asymmetric cell division of neural stem cells and their derivative progenitor cells. Cerebellar granule cells are the most abundant neurons in the CNS, and are generated by intensive cell division of granule cell precursors (GCPs) during postnatal development ...
Kie, Nakashima +2 more
openaire +2 more sources
Labeling of Precursor Granule Cells in the Cerebellum by ex vivo Electroporation
Bio-Protocol, 2013 This protocol will be useful to introduce the genes of interest into the cerebellar granule cells at early stages of development. Since the granule cell precursors are localized in the external granule layer before migration, DNA plasmids can be ...
Aya Ito-Ishida
doaj +1 more source
Differential Structural Development of Adult-Born Septal Hippocampal Granule Cells in the Thy1-GFP Mouse, Nuclear Size as a New Index of Maturation. [PDF]
PLoS ONE, 2015 Adult neurogenesis is frequently studied in the mouse hippocampus. We examined the morphological development of adult-born, immature granule cells in the suprapyramidal blade of the septal dentate gyrus over the period of 7-77 days after mitosis with ...
Tijana Radic +4 more
doaj +1 more source
Brain Sciences, 2020 Preterm birth, a major contributor to infant mortality and morbidity, impairs development of the cerebellum, the brain region involved in cognitive processing and motor function.
Daniel Chizhikov +2 more
doaj +1 more source