Results 51 to 60 of about 5,501,717 (307)
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Dynamic connectivity in the mitral cell-granule cell microcircuit.
, 2018 The interactions between excitatory mitral cells and inhibitory granule cells are critical for the regulation of olfactory bulb activity. Here we review anatomical and physiological data on the mitral cell-granule cell circuit and provide a quantitative ...
Veronica Egger (5063960) +1 more
core +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Frontiers in NeuroanatomySemilunar granule cells in the dentate gyrus represent a distinct type of granule cell, distinguished by their unique morphology and physiology. These cells are located within the inner molecular layer and the upper juxta-granule cell layer of the ...
Laura Rovira-Esteban +8 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Regulation of cerebellar network development by granule cells and their molecules
Frontiers in Molecular Neuroscience, 2023 The well-organized cerebellar structures and neuronal networks are likely crucial for their functions in motor coordination, motor learning, cognition, and emotion.
Muwoong Kim +7 more
doaj +1 more source
Structured sampling of molecularly classified mossy fiber inputs by cerebellar granule cells
Frontiers in Computational NeuroscienceThe cerebellar granule cell layer receives mossy fiber inputs from diverse brain regions, yet the principles governing how individual granule cells sample distinct types of inputs remain poorly understood. Using a volumetric correlated light and electron
Xiaomeng Han +2 more
doaj +1 more source
Cerebellar Patterning Defects in Mutant Mice
Frontiers in Neuroscience, 2021 The cerebellar cortex is highly compartmentalized and serves as a remarkable model for pattern formation throughout the brain. In brief, the adult cerebellar cortex is subdivided into five anteroposterior units—transverse zones—and subsequently, each ...
Richard Hawkes
doaj +1 more source
Camillo Golgi on Cerebellar Granule Cells [PDF]
The Cerebellum, 2012 info:eu-repo/semantics ...
Mazzarello, Paolo +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source