Results 11 to 20 of about 5,501,717 (307)
Hilar mossy cell circuitry controlling dentate granule cell excitability [PDF]
Frontiers in Neural Circuits, 2013 Glutamatergic hilar mossy cells of the dentate gyrus can either excite or inhibit distant granule cells, depending on whether their direct excitatory projections to granule cells or their projections to local inhibitory interneurons dominate. However, it
Seiichiro eJinde +2 more
doaj +2 more sources
Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics Investigation of Neurodevelopmental Migratory Pathways [PDF]
Frontiers in Cellular Neuroscience, 2020 Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Joan Y. W. Liu +9 more
doaj +2 more sources
, 2013 The cerebellar granule cells are the most numerous neurons of the brain. They are also among the most simple by emitting just four short unbranched dendrites innervated by the mossy fibers and a thin axon that branches into the parallel fibers. The granule cells are the only excitatory neurons of the cerebellum and receive inhibition uniquely through ...
Egidio D’Angelo, D'ANGELO, EGIDIO UGO
openaire +3 more sources
Granule Cells in the CA3 Area [PDF]
Journal of Neuroscience, 2010 A fundamental property of neuronal networks in Ammon's horn is that each area comprises a single glutamatergic cell population and various types of GABAergic neurons. Here we describe an exception to this rule, in the form of granule cells that reside within the CA3 area and function as glutamatergic nonprincipal cells with distinct properties.
János, Szabadics +4 more
openaire +2 more sources
PLoS ONE, 2022 Mast cells are tissue-resident immune cells that have numerous cytoplasmic granules which contain preformed pro-inflammatory mediators. Upon antigen stimulation, sensitized mast cells undergo profound changes to their morphology and rapidly release ...
Jeremies Ibanga +3 more
doaj +2 more sources
RNA Granules in Germ Cells [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 "Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and ...
Ekaterina, Voronina +3 more
openaire +2 more sources
Bidirectional GABAergic control of AP firing in newly-generated young granule cells of the adult hippocampus [PDF]
, 2015 Gamma-aminobutyric acid (GABA) is the first transmitter which provides synaptic input to newly generated neurons. In the first 2-3 weeks after mitosis, young neurons show an elevated intracellular chloride concentration due to the expression of the NKCC1
Heigele, Stefanie
core +1 more source
Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures [PDF]
, 2012 During postnatal development hippocampal dentate granule cells (GCs) often extend dendrites from the basal pole of their cell bodies into the hilar region. These so-called hilar basal dendrites (hBD) usually regress with maturation.
Gerlind Schuldt +26 more
core +1 more source
Task-dependent optimal representations for cerebellar learning
eLife, 2023 The cerebellar granule cell layer has inspired numerous theoretical models of neural representations that support learned behaviors, beginning with the work of Marr and Albus.
Marjorie Xie +3 more
doaj +1 more source
Characterization of granule-like structures in non-endocrine cells [PDF]
, 2006 All eukaryotic cells have transport pathways to constitutively secrete proteins. Endocrine, neuroendocrine, and exocrine cells in addition have a regulated secretory pathway that serves the controlled release of hormones, neuropeptides or digestive ...
Stettler, Hansruedi
core +1 more source