Results 21 to 30 of about 5,501,717 (307)

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

open access: yes, 2020
Immune-modulating therapies have revolutionized the treatment of chronic diseases, particularly cancer. However, their success is restricted and there is a need to identify new therapeutic targets. Here, we show that natural killer cell granule protein 7
McEnroe, Benjamin A   +14 more
core   +2 more sources

Entorhinal denervation induces homeostatic synaptic scaling of excitatory postsynapses of dentate granule cells in mouse organotypic slice cultures [PDF]

open access: yes, 2012
Denervation-induced changes in excitatory synaptic strength were studied following entorhinal deafferentation of hippocampal granule cells in mature (≥3 weeks old) mouse organotypic entorhino-hippocampal slice cultures.
Roeper, Jochen   +23 more
core   +1 more source

Purkinje cell responses during diverse Granule cell plasticity scenarios

open access: yes, 2022
Purkinje cell responses during diverse Granule cell plasticity ...
Robin De Schepper
core   +1 more source

Mitral cell spike synchrony modulated by dendrodendritic synapse location

open access: yesFrontiers in Computational Neuroscience, 2012
On their long lateral dendrites, mitral cells of the olfactory bulb form dendrodendritic synapses with large populations of granule cell interneurons. The mitral-granule cell microcircuit operating through these reciprocal synapses has been implicated in
Thomas S McTavish   +3 more
doaj   +1 more source

Short-Term Plasticity in Cortical GABAergic Synapses on Olfactory Bulb Granule Cells Is Modulated by Endocannabinoids

open access: yesFrontiers in Cellular Neuroscience, 2021
Olfactory bulb and higher processing areas are synaptically interconnected, providing rapid regulation of olfactory bulb circuit dynamics and sensory processing. Short-term plasticity changes at any of these synapses could modulate sensory processing and
Fu-Wen Zhou, Adam C. Puche
doaj   +1 more source

APP Expression in Primary Neuronal Cell Cultures fromP6 Mice during in vitro Differentiation [PDF]

open access: yes, 1993
Primary neuronal cell cultures from P6 mice were investigated in order to study amyloid protein precursor (APP) gene expression in differentiating neurons.
Sandbrink, R.   +5 more
core   +1 more source

Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus

open access: yesMolecular Brain, 2010
New granule cells are continuously generated in the dentate gyrus of the adult hippocampus. During granule cell maturation, the mechanisms that differentiate new cells not only describe the degree of cell differentiation, but also crucially regulate the ...
Ohira, Koji   +7 more
doaj   +1 more source

Enzymes of the Mast Cell Granule

open access: yesJournal of Investigative Dermatology, 1980
Rat mast cell granules contain a spectrum of enzymes as established by histochemical techniques and subcellular fractionation. However, 35% of the beta-glucuronidase, 30% of the beta-D-galactosidase, 14% of the beta-hexosaminidase and all of the acid phosphatase is not available for immunologic release from purified rat serosal mast cells, suggesting ...
Schwartz, Lawrence B., Frank Austen, K.
openaire   +2 more sources

Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input

open access: yesFrontiers in Integrative Neuroscience, 2014
Golgi cells (GoCs) are specialized interneurons that provide inhibitory input to granule cells in the cerebellar cortex. GoCs are pacemaker neurons that spontaneously fire action potentials, triggering spontaneous inhibitory postsynaptic currents in ...
Paolo eBotta   +2 more
doaj   +1 more source

Plasticity in mammalian somatosensory cerebellar maps [PDF]

open access: yes, 1996
The organization of sensory maps in mammalian brains can change following peripheral injury or experience. Such plasticity has been demonstrated for somatotopic somatosensory maps in various cortical and subcortical areas. In contrast to somatotopic maps,
Morissette, Josee
core   +1 more source

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