Results 21 to 30 of about 178,493 (310)
Generation and characterization of an Nse-CreERT2 transgenic line suitable for inducible gene manipulation in cerebellar granule cells. [PDF]
PLoS ONE, 2014 We created an Nse-CreERT2 mouse line expressing the tamoxifen-inducible CreERT2 recombinase under the control of the neuron-specific enolase (Nse) promoter.
Theresa Pohlkamp +7 more
doaj +1 more source
Granule Cells in the CA3 Area [PDF]
Journal of Neuroscience, 2010 A fundamental property of neuronal networks in Ammon's horn is that each area comprises a single glutamatergic cell population and various types of GABAergic neurons. Here we describe an exception to this rule, in the form of granule cells that reside within the CA3 area and function as glutamatergic nonprincipal cells with distinct properties.
János, Szabadics +4 more
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The periglomerular cell of the olfactory bulb and its role in controlling mitral cell spiking: a computational model. [PDF]
PLoS ONE, 2013 Interneurons in the olfactory bulb are key elements of odor processing but their roles have not yet being fully understood. Two types of inhibitory interneurons, periglomerular and granule cells, act at two different levels within the olfactory bulb and ...
Denise Arruda +2 more
doaj +1 more source
Origins, Development, and Compartmentation of the Granule Cells of the Cerebellum
Frontiers in Neural Circuits, 2021 Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the brain: at least 99% of all cerebellar neurons are granule cells.
G. Giacomo Consalez +3 more
doaj +1 more source
PLoS ONE, 2022 Mast cells are tissue-resident immune cells that have numerous cytoplasmic granules which contain preformed pro-inflammatory mediators. Upon antigen stimulation, sensitized mast cells undergo profound changes to their morphology and rapidly release ...
Jeremies Ibanga +3 more
doaj +2 more sources
RNA Granules in Germ Cells [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 "Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and ...
Ekaterina, Voronina +3 more
openaire +2 more sources
Task-dependent optimal representations for cerebellar learning
eLife, 2023 The cerebellar granule cell layer has inspired numerous theoretical models of neural representations that support learned behaviors, beginning with the work of Marr and Albus.
Marjorie Xie +3 more
doaj +1 more source
Bidirectional GABAergic control of AP firing in newly-generated young granule cells of the adult hippocampus [PDF]
, 2015 Gamma-aminobutyric acid (GABA) is the first transmitter which provides synaptic input to newly generated neurons. In the first 2-3 weeks after mitosis, young neurons show an elevated intracellular chloride concentration due to the expression of the NKCC1
Heigele, Stefanie
core +1 more source
Characterization of granule-like structures in non-endocrine cells [PDF]
, 2006 All eukaryotic cells have transport pathways to constitutively secrete proteins. Endocrine, neuroendocrine, and exocrine cells in addition have a regulated secretory pathway that serves the controlled release of hormones, neuropeptides or digestive ...
Stettler, Hansruedi
core +1 more source
Mitral cell spike synchrony modulated by dendrodendritic synapse location
Frontiers in Computational Neuroscience, 2012 On their long lateral dendrites, mitral cells of the olfactory bulb form dendrodendritic synapses with large populations of granule cell interneurons. The mitral-granule cell microcircuit operating through these reciprocal synapses has been implicated in
Thomas S McTavish +3 more
doaj +1 more source