Results 1 to 10 of about 40,561 (247)

Granulosa cell tumor of the ovary: a clinicopathological study of six cases

open access: diamondJournal of Pathology of Nepal, 2011
Background: Ovarian granulosa cell tumors are rare malignant neoplasms that originate from the sexcord stromal cells of the ovary. The study aims to collate data of all granulosa cell tumors diagnosed in Tribhuvan University Teaching Hospital over the ...
RC Adhikari, A Jha, G Shayami
doaj   +3 more sources

Unicystic Granulosa Cell Tumor [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2015
Granulosa cell tumors are the most frequent sex cord stromal tumor and account for approximately 5% of all primary ovarian tumors. About 5% occur before puberty and 40% occur in the menopausal age group; however, these tumors have an indolent biological behavior [1].
Arun Prabhakaran   +3 more
openaire   +3 more sources

Juvenile Granulosa Cell Tumour: Anaplastic Variant with Omental Deposits [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Juvenile Granulosa Cell Tumour (JGCT) of ovary represents a small fraction of all primary ovarian malignancies. It is a subtype of granulosa cell tumour that is almost always found during the first three decades of life.
Anuradha C.K. Rao   +2 more
doaj   +1 more source

BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing

open access: yesJournal of Ovarian Research, 2023
Background Granulosa cell proliferation and differentiation are essential for follicle development. Breast cancer amplified sequence 2 (BCAS2) is necessary for spermatogenesis, oocyte development, and maintaining the genome integrity of early embryos in ...
Xiaohong Yao   +11 more
doaj   +1 more source

Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries

open access: yesJournal of Ovarian Research, 2023
Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with androgen excess and anovulatory infertility. In the current study, we investigated the role of dihydrotestosterone-induced exosomal miR-379-5p release in determining
Reza Salehi   +19 more
doaj   +1 more source

The Cultivation of Human Granulosa Cells [PDF]

open access: yesActa Medica (Hradec Kralove, Czech Republic), 2008
The major functions of granulosa cells (GCs) include the production of steroids, as well as a myriad of growth factors to interact with the oocyte during its development within the ovarian follicle. Also FSH stimulates GCs to convert androgens (coming from the thecal cells) to estradiol by aromatase.
Benjamin Visek   +7 more
openaire   +3 more sources

GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. [PDF]

open access: yesPLoS Genetics, 2017
Folliculogenesis is a progressive and highly regulated process, which is essential to provide ova for later reproductive life, requires the bidirectional communication between the oocyte and granulosa cells.
Chen Jiang   +12 more
doaj   +1 more source

PRMT5 regulates ovarian follicle development by facilitating Wt1 translation

open access: yeseLife, 2021
Protein arginine methyltransferase 5 (Prmt5) is the major type II enzyme responsible for symmetric dimethylation of arginine. Here, we found that PRMT5 was expressed at high level in ovarian granulosa cells of growing follicles.
Min Chen   +8 more
doaj   +1 more source

Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2018
Gynandroblastoma is an extremely rare sex cord-stromal tumor with both female (granulosa cell tumor) and male (Sertoli-Leydig cell tumor) elements. Juvenile granulosa cell tumors are also very rare and are so named because they usually occur in children ...
Nu Ri Jang   +5 more
doaj   +1 more source

Enxtraoviarian granulosa cell tumor: a case report

open access: yesThe Pan African Medical Journal, 2016
Extraovarian granulosa cell tumor (GCT) is a very unusually tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge.
Saad Rifki Jai   +4 more
doaj   +1 more source

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