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Primary extraovarian adult granulosa cell tumor of the greater omentum: a case report and literature review [PDF]

Frontiers in Oncology
Extraovarian adult granulosa cell tumors are rare. The diagnosis of extraovarian adult granulosa cell tumors is challenging. Here we presented a case of extraovarian adult granulosa cell tumor originating in the greater omentum.
Ying Zeng, Liang Lv, Liping Luo
doaj   +2 more sources

Granulosa cell tumor patients presenting with acute abdomen: a case series [PDF]

Gynecologic Oncology Reports
Objective: To highlight the unique clinical presentation of acute abdomen in granulosa cell tumor patients. Methods: In a multicenter cohort study of adult-type granulosa cell tumors, women presenting with an acute abdomen at diagnosis were identified ...
Geertruid J. Brink, Jolijn W. Groeneweg, Ariane A. Sickinghe, Christianne A.R. Lok, Hans W. Nijman, Jurgen M.J. Piek, Ward Hofhuis, Eva Maria Roes, Luc R.C.W. van Lonkhuijzen, Cor D. de Kroon, Eelke H. Gort, Petronella O. Witteveen, Ronald P. Zweemer   +12 more
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RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice [PDF]

Advanced Science
The generation of mature oocytes, a cornerstone of reproduction, relies on the coordinated interactions between oocytes and surrounding follicular somatic cells.
Yingmei Wang, Hongjiang Li, Liji You, Shuhui Wang, Jinglei Bie, Ziyang Su, Lanying Shi, You‐Qiang Su   +7 more
doaj   +2 more sources

FGF12 regulates cell cycle gene expression and promotes follicular granulosa cell proliferation through ERK phosphorylation in geese

Poultry Science, 2023
: The granulosa cells play an important role in the fate of follicular development or atresia in poultry. Fibroblast growth factor 12 (FGF12) is downregulated in atretic follicles and may be involved in regulating granulosa cell survival in previous ...
Wanli Yang, Shiqi Yu, Jinzhou Peng, Penghui Chang, Xingyong Chen   +4 more
doaj   +1 more source

Recurrent granulosa cell tumor of the retroperitoneum during the COVID-19 Pandemic

Gynecologic Oncology Reports, 2022
Extraovarian granulosa cell tumors are rare with very few cases of isolated retroperitoneal granulosa cell tumors reported in the literature. Granulosa cell tumors are notorious for late recurrences and patients should have long term oncologic follow up.
Yasmin Abedin, Upasana Madan, Deena Graham, Mira C. Hellmann   +3 more
doaj   +1 more source

Juvenile Granulosa Cell Tumour: Anaplastic Variant with Omental Deposits [PDF]

Journal of Clinical and Diagnostic Research, 2016
Juvenile Granulosa Cell Tumour (JGCT) of ovary represents a small fraction of all primary ovarian malignancies. It is a subtype of granulosa cell tumour that is almost always found during the first three decades of life.
Anuradha C.K. Rao, Manjari Kishore, Vidya Monappa   +2 more
doaj   +1 more source

BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing

Journal of Ovarian Research, 2023
Background Granulosa cell proliferation and differentiation are essential for follicle development. Breast cancer amplified sequence 2 (BCAS2) is necessary for spermatogenesis, oocyte development, and maintaining the genome integrity of early embryos in ...
Xiaohong Yao, Chaofan Wang, Longjie Sun, Lu Yan, Xuexue Chen, Zheng Lv, Xiaomei Xie, Shuang Tian, Wenbo liu, Lei Li, Hua Zhang, Jiali Liu   +11 more
doaj   +1 more source

Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries

Journal of Ovarian Research, 2023
Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with androgen excess and anovulatory infertility. In the current study, we investigated the role of dihydrotestosterone-induced exosomal miR-379-5p release in determining
Reza Salehi, Brandon A. Wyse, Meshach Asare-Werehene, Fereshteh Esfandiarinezhad, Atefeh Abedini, Bo Pan, Yoko Urata, Alex Gutsol, Jose L. Vinas, Sahar Jahangiri, Kai Xue, Yunping Xue, Kevin D. Burns, Barbara Vanderhyden, Julang Li, Yutaka Osuga, Dylan Burger, Seang-Lin Tan, Clifford L. Librach, Benjamin K. Tsang   +19 more
doaj   +1 more source

Unicystic Granulosa Cell Tumor [PDF]

Journal of Pathology and Translational Medicine, 2015
Granulosa cell tumors are the most frequent sex cord stromal tumor and account for approximately 5% of all primary ovarian tumors. About 5% occur before puberty and 40% occur in the menopausal age group; however, these tumors have an indolent biological behavior [1].
Nalli R. Sumitra Devi, Sathya Lakshmi Ramu, Arun Prabhakaran, Deepa Devi Govindaswamy   +3 more
openaire   +3 more sources

Torsion of juvenile granulosa cell ovarian tumor

Journal of Pediatric Surgery Case Reports, 2022
Juvenile granulosa cell tumor (JGCT), which is one of the sex cord-stromal tumors of the ovary, is a rare malignancy of childhood. Juvenile type is a rare form that accounts for 5% of granulosa cell tumors. Isosexual precocious puberty is the most common
Şenay Kurtuluş, Bülent Demir, Nilüfer Aylanç   +2 more
doaj   +1 more source