Results 61 to 70 of about 31,762 (231)

Fertility-Preserving Surgery in a Young Nulligravid Woman with Bilateral Coexistence of a Granulosa Cell Tumor with a Teratoma

open access: yesCase Reports in Obstetrics and Gynecology, 2023
Background. The coexistence of a granulosa cell tumor with a teratoma is extremely rare and impossible to diagnose preoperatively. For most patients with advanced age and stage, the standard treatment is hysterectomy and bilateral salpingo-oophorectomy ...
Pham Ba Nha   +3 more
doaj   +1 more source

Perturbations in Lineage Specification of Granulosa and Theca Cells May Alter Corpus Luteum Formation and Function [PDF]

open access: yes, 2019
Anovulation is a major cause of infertility, and it is the major leading reproductive disorder in mammalian females. Without ovulation, an oocyte is not released from the ovarian follicle to be fertilized and a corpus luteum is not formed.
Abedel-Majed, Mohamed A.   +3 more
core   +1 more source

Species-specific differences in follicular antral sizes result from diffusion-based limitations on the thickness of the granulosa cell layer

open access: yes, 2013
The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte.
Bächler, M.   +3 more
core   +1 more source

Nuclear localization of β-catenin in Sertoli cell tumors and other sex cord–stromal tumors of the testis: an immunohistochemical study of 87 cases [PDF]

open access: yes, 2015
The diagnosis and subclassification of Sertoli cell tumors (SCT) of the testis are often challenging to general surgical pathologists because of the rarity of the tumors. Immunohistochemical study to date has limited diagnostic value.
Ulbright, Thomas M., Zhang, Chen
core   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

open access: yesInterdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li   +10 more
wiley   +1 more source

The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle. [PDF]

open access: yes, 2003
In the mammalian ovary, great interest in the expression and function of the bone morphogenetic protein (BMP) family has been recently generated from evidence of their critical role in determining folliculogenesis and female fertility.
Erickson, Gregory F, Shimasaki, Shunichi
core   +3 more sources

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer

open access: yesWorld Journal of Surgical Oncology, 2010
Background Adult granulosa cell tumor associated with antecedent use of tamoxifen as adjuvant hormonotherapy for breast cancer is rare. The pathogenesis of this occurrence remains difficult to explain.
Abahssain Halima   +4 more
doaj   +1 more source

Extragonadal LH/hCG action-Not yet time to rewrite textbooks [PDF]

open access: yes, 2007
Gonadotropins are indispensable in both sexes in the regulation of gonadal sex steroid production and gametogenesis. In addition to their well-established classical actions, numerous recent publications have indicated the presence and function of ...
Ahtiainen, Petteri   +5 more
core   +3 more sources

Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells [PDF]

open access: yes, 2016
Expression of follicle-stimulation hormone receptor (FSHR) is confined to gonads and at low levels to some extragonadal tissues like human umbilical vein endothelial cells (HUVEC). FSH-FSHR signaling was shown to promote HUVEC angiogenesis and thereafter
Akerfelt, Malin   +11 more
core   +1 more source

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