Results 21 to 30 of about 49,325 (246)

Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome

open access: yesFrontiers in Endocrinology, 2022
The mechanisms underlining pathogenesis of polycystic ovary syndrome (PCOS) remain largely unknown. Dysfunction of ovarian granulosa cells plays an important role.
Yan Deng   +14 more
doaj   +1 more source

TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways. [PDF]

open access: yesPLoS ONE, 2015
Connective tissue growth factor (CTGF), which is also called CCN2, is a secreted matricellular protein. CTGF regulates various important cellular functions by interacting with multiple molecules in the microenvironment.
Jung-Chien Cheng   +4 more
doaj   +1 more source

Extraovarian Granulosa Cell Tumor

open access: yesYonsei Medical Journal, 2001
A 54-year-old woman was admitted to our hospital complaining of postcoital bleeding. Sonography of the abdomen showed a 8.2 x 8.9 cm-sized solid heterogeneous mass occupying the cul-de-sac, which appeared to be in no way connected with the ovary. On exploratory laparotomy, the tumor mass protruded from the posterolateral retroperitoneum of the pelvic ...
S H, Kim   +6 more
openaire   +3 more sources

Extraovarian granulosa cell tumor

open access: yesIndian Journal of Pathology and Microbiology, 2009
Extraovarian granulosa cell tumor (GCT) is a very uncommon tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. One such rare case of extraovarian GCT was encountered in a 58-year-old female who presented with a large intraabdominal lump.
Paul Prabir   +3 more
openaire   +3 more sources

Movento influences development of granulosa cells and ovarian follicles and FoxO1 and Vnn1 gene expression in BALB/c mice [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2016
Objective(s): Pesticides has wide range of infertility in female reproductive. This study was done to evaluate the effect of movento pesticide on development of granulosa cells and ovarian follicles and FoxO1 and Vnn1 gene expression in BALB/c mice ...
Sakineh Kaboli Kafshgiri   +4 more
doaj   +1 more source

Granulosa Cells: Central Regulators of Female Fertility

open access: yesEndocrines
Background: Granulosa cells are somatic cells within the ovarian follicle. As the primary site of estradiol production, they are critical regulators of several aspects of female reproduction.
Luis Fernando Schütz   +1 more
doaj   +1 more source

GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. [PDF]

open access: yesPLoS Genetics, 2017
Folliculogenesis is a progressive and highly regulated process, which is essential to provide ova for later reproductive life, requires the bidirectional communication between the oocyte and granulosa cells.
Chen Jiang   +12 more
doaj   +1 more source

Regulatory Mechanisms Underlying the Expression of Prolactin Receptor in Chicken Granulosa Cells. [PDF]

open access: yesPLoS ONE, 2017
Prolactin (PRL) has both pro- and anti-gonadal roles in the regulation of avian ovarian functions through its interaction with the receptor (PRLR).
Shenqiang Hu   +2 more
doaj   +1 more source

CNOT6L regulates energy metabolism in the ovarian granulosa cells associated with polycystic ovary syndrome

open access: yesFrontiers in Cell and Developmental Biology
The endocrine functions exerted by ovarian granulosa cells (GCs) are crucial factors in maintaining follicle development, as oocyte development relies on providing energy substrates and cytokines by ovarian granulosa cells.
Shan Han   +7 more
doaj   +1 more source

Transcriptional activation of the mouse Scd2 gene by interdependent enhancers and long noncoding RNAs in ovarian granulosa cells

open access: yesThe Journal of Reproduction and Development, 2020
Specific gene expression in granulosa cells is key for the function of ovary, but the molecular mechanism of transcriptional activation is not well studied.
Shota MAYAMA   +4 more
doaj   +1 more source

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