Results 31 to 40 of about 10,360,699 (193)
International Journal on Biological Sciences, 2018 Zearalenone (ZEA), a metabolite of Fusarium fungi, is commonly found on moldy grains. Because it can competitively combine to estrogen receptor to disrupt estrogenic signaling, it has been reported to have serious adverse effects on animal reproduction ...
Xue-Lian Liu +9 more
semanticscholar +1 more source
Granulosa Cells: Central Regulators of Female Fertility
EndocrinesBackground: Granulosa cells are somatic cells within the ovarian follicle. As the primary site of estradiol production, they are critical regulators of several aspects of female reproduction.
Luis Fernando Schütz +1 more
doaj +1 more source
Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma
OncoTarget, 2017 Reactive oxygen species (ROS) play important roles in follicular development and survival. Granulosa cell death is associated with increased ROS, but the mechanism of granulosa cell death induced by ROS is not clear. In order to define the molecular link
Hongyan Yang +3 more
semanticscholar +1 more source
Extraovarian Granulosa Cell Tumor
Yonsei Medical Journal, 2001 A 54-year-old woman was admitted to our hospital complaining of postcoital bleeding. Sonography of the abdomen showed a 8.2 x 8.9 cm-sized solid heterogeneous mass occupying the cul-de-sac, which appeared to be in no way connected with the ovary. On exploratory laparotomy, the tumor mass protruded from the posterolateral retroperitoneum of the pelvic ...
Woong Yun Chung +6 more
openaire +4 more sources
Juvenile granulosa cell tumor [PDF]
Asian Journal of Oncology, 2016 The differential diagnosis for precocious puberty in a young female includes peripheral causes. This case report documents a rare cause of isosexual precocious puberty, a juvenile granulosa cell tumour of the ovary–and a brief literature review.
S. Unmesh +4 more
openaire +2 more sources
International Journal of Molecular Sciences, 2023 Granulosa cells are crucial for the establishment and maintenance of bidirectional communication among oocytes. Various intercellular material exchange modes, including paracrine and gap junction, are used between them to achieve the efficient delivery ...
Chen-Hua Zhang, Xiang-Yi Liu, Jing Wang
semanticscholar +1 more source
Frontiers in Cell and Developmental BiologyThe endocrine functions exerted by ovarian granulosa cells (GCs) are crucial factors in maintaining follicle development, as oocyte development relies on providing energy substrates and cytokines by ovarian granulosa cells.
Shan Han +7 more
doaj +1 more source
Estrogen receptors in granulosa cells govern meiotic resumption of pre-ovulatory oocytes in mammals
Cell Death and Disease, 2017 In mammals, oocytes are arrested at the diplotene stage of meiosis I until the pre-ovulatory luteinizing hormone (LH) surge triggers meiotic resumption through the signals in follicular granulosa cells.
Wei Liu +12 more
semanticscholar +1 more source
Journal of Ovarian Research, 2020 Background We elucidated the role of specific MicroRNAs (miRNAs) in the development of polycystic ovary syndrome (PCOS) and explained the changes in the proliferation of granulosa cells. Excised ovarian cortex specimens were collected for miRNA profiling
Zhengfang Xiong +6 more
doaj +1 more source
Scientific Reports, 2017 Recent studies report the involvement of intra-ovarian factors, such as inflammation and oxidative stress, in the pathophysiology of polycystic ovary syndrome (PCOS), the most common endocrine disorder of reproductive age women. Endoplasmic reticulum (ER)
Nozomi Takahashi +15 more
semanticscholar +1 more source