Results 221 to 230 of about 94,825 (337)

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

Immunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng, Eimear K. Ryan, Michael Bennett, Christy Clutter, Jackson G. Cacioppo, Jeffrey Aubé, Andy E. Hogan, Daniel T. Leung   +7 more
wiley   +1 more source

Les liaisons dangereuses: Immunological synapse formation in animals and plants [PDF]

, 2008
Kwon, C., Panstruga, R., Schulze-Lefert, P.   +2 more
core   +1 more source

Human tolerogenic dendritic cell subtypes exert divergent effects on induction of cytotoxic CD4⁺ T cells. [PDF]

Front Immunol
Barran G, Naamane N, Baru AM, Anderson AE, Falconer J, Hilkens CMU.   +5 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Changes in circulating NK and innate-like T cells in type 1 and type 2 diabetes. [PDF]

Front Immunol
Loguinova M, Sergeev N, Samsonova M, Sorokina A, Grebennikov D, Golodnikov I, Goncharenko A, Bocharov G, Laptev D, Khusainova R, Minniakhmetov I, Shestakova M, Dedov I, Mokrysheva N.   +13 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Development of Single-Molecule Enzyme Activity Assay for Serine Hydrolases Using Activity-Based Protein Labeling Probes. [PDF]

Small Methods
Ishii S, Minoda M, Mizuno T, Iwasaka T, Kusuhara H, Honda K, Urano Y, Komatsu T.   +7 more
europepmc   +1 more source

Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death Program.

Cell, 2017
Farokh Dotiwala, S. S. Santara, Andres A Binker-Cosen, Bo Li, Sriram Chandrasekaran, J. Lieberman   +5 more
semanticscholar   +1 more source

A unique cellular and molecular microenvironment is present in tertiary lymphoid organs of patients with spontaneous prostate cancer regression [PDF]

, 2017
de la Luz Garcia-Hernandez, Maria, Espinosa-Gonzalez, Ricardo, Kast, W. Martin, Khader, Shabaana A, Rangel-Moreno, Javier, Uribe-Uribe, Norma Ofelia   +5 more
core   +2 more sources

Quantitative dynamic granzyme B PET imaging to characterize novel combination immunotherapy response in preclinical glioblastoma models. [PDF]

Theranostics
Gallegos CA, Lu Y, Song PN, Queiroz R, Akca U, Sridhar S, Bartels JL, Zhang Y, Li L, Warram JM, Lapi SE, Larimer BM, Markert JM, Sorace AG.   +13 more
europepmc   +1 more source