Results 231 to 240 of about 94,825 (337)

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

The mechanism regulating the cytotoxicity of γδ T cells activated by mycobacterium tuberculosis heat-resistant antigen based on RNA-seq analysis. [PDF]

Front Immunol
Song Y, Guo F, Dai H, Zhou X, Dong S, Zhang H, Qian Z, Li B, Wang X, Xu T, Wang H.   +10 more
europepmc   +1 more source

Programmable Antigen‐Specific Immunity via Self‐Adjuvanting Nanovaccines Co‐Delivering Immune Modulators

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito, Yoshiyuki Manabe, Shino Ohshima, Masatoshi Maeki, Manabu Tokeshi, Hiroshi Inaba, Kazunori Matsuura, Kazuya Kabayama, Yoshie Kametani, Koichi Fukase   +9 more
wiley   +2 more sources

CD30 Expression in Neoplastic Mast Cells and the Presence of CD30+, CD3+, and PAX‐5+ Tumour‐Infiltrating Lymphocytes as Prognostic Markers in Canine Cutaneous Mast Cell Tumours

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine cutaneous mast cell tumour (MCT) is the most common skin neoplasm in dogs, with histopathology serving as both the diagnostic and primary prognostic tool. However, identifying reliable biomarkers is essential for improving clinical decision‐making.
Fernanda Ramalho Ramos, Janayna Maria Parente Serafim, Bethânia Almeida Gouveia, Pedro Luiz Porfirio Xavier, Juliano Rodrigues Sangalli, Heidge Fukumasu, Ricardo de Francisco Strefezzi   +6 more
wiley   +1 more source

Granzyme B-producing B cells: a bidirectional relationship with breast cancer cells and implications for immunotherapy. [PDF]

Am J Clin Exp Immunol
Hakimi H, Mehdipour F, Samadi M, Balouchi Anaraki S, Rasolmali R, Talei AR, Ghaderi A.   +6 more
europepmc   +1 more source

Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging

Journal of Immunology, 2018
Robert A. Campbell, Z. Franks, A. Bhatnagar, J. Rowley, B. Manne, M. Supiano, H. Schwertz, A. Weyrich, M. Rondina   +8 more
semanticscholar   +1 more source

Cytotoxic CD4⁺ T cells: origin, biological functions, diseases and therapeutic targets. [PDF]

Signal Transduct Target Ther
Lai L, Ran S, Li Y, Cui J, Zhang X, Yu J, Zou Y, Zhou C, Xia J, Wu J.   +9 more
europepmc   +1 more source

CD56+/CD16- Natural Killer cells expressing the inflammatory protease granzyme A are enriched in synovial fluid from patients with osteoarthritis.

Osteoarthritis and Cartilage, 2017
P. Jaime, N. Garcia-Guerrero, R. Estella, J. Pardo, F. García-Álvarez, L. Martínez-Lostao   +5 more
semanticscholar   +1 more source

C‐X‐C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8+ T cells within the tumor microenvironment

International Journal of Cancer, Volume 158, Issue 6, Page 1740-1754, 15 March 2026.
What's new? In addition to governing daily variations in biological activity, the circadian clock regulates immune cell migration into tumors. Whether this influence extends to immune cell localization within the tumor microenvironment (TME) is unknown. Here, using cell and animal models, the authors investigated immune cell distribution within the TME
Akito Tsuruta, Marina Fujimoto, Yasuha Hiraoka, Aoi Taniguchi, Yuki Shiiba, Takuto Inoki, Tomoaki Yamauchi, Yuya Yoshida, Naoya Matsunaga, Shigehiro Ohdo, Satoru Koyanagi   +10 more
wiley   +1 more source

<i>Epimedium brevicornu</i> Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway. [PDF]

Front Pharmacol
Liu L, Zhan X, Wang X, Wen J, He C, Chen X, Guo Y, Wang X, Li L, Cheng H, Bai Z, Xiao X.   +11 more
europepmc   +1 more source