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Expression of Granzyme B and Perforin in Multiple Myeloma
Acta Haematologica, 2001Multiple myeloma (MM) remains an incurable disease by conventional therapy. MM tumor cells evade the immune system and can induce immunosuppression by producing immunomodifying agents such as TGF-β, FasL, vascular endothelial growth factor and Muc-1. In the present study, we show that bone marrow cells from a patient suffering from MM IgG/k type, stage
I, Xagoraris +5 more
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In vivo bioluminescence imaging of granzyme B activity in tumor response to cancer immunotherapy
Cell Chemical Biology, 2022Preethi Bala Balakrishnan +2 more
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Granzyme B as a therapeutic target: an update in 2022
Expert Opinion on Therapeutic Targets, 2022David Granville +2 more
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Granzyme B Induces Smooth Muscle Cell Apoptosis in the Absence of Perforin
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004David Granville +2 more
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