Results 81 to 90 of about 414,825 (300)

Developing Deadly Skies [PDF]

open access: yes, 2016
The Canadian War Museum’s exhibition Deadly Skies – Air War, 1914-1918 examines the first air war from the perspective of nine international participants representing Canada, the United States, France, Great Britain, and Germany.
Maker, John
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Umberto Eco’s The Mysterious Flame of Queen Loana: A conduit for culture, consciousness and cognition

open access: yesInkanyiso, 2010
Eco’s novel describes the popular culture of the Italian fascist period, by deconstructing signs, symbols and signals from a particular period in the lives of both the author and his protagonist.
Marie Spruyt
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

MODULATION AS A MULTIMODAL TRANSLATION STRATEGY OF GRAPHIC NOVEL PERSEPOLIS BY M. SATRAPI [PDF]

open access: yesAlfred Nobel University Journal of Philology
The article presents a specific perspective on modulation as a universal strategy for translating multimodal graphic novel, while exploring the interplay between visual and verbal elements in meaning construction.
Anna V. Khodorenko
doaj   +1 more source

The English Bugaboo - Cruikshank to Talbot [PDF]

open access: yes, 2011
This post examines some aspects of the British diachronic illustrative tradition in connection with Talbot's Alice in Sunderland (2007). In this post, James Baker argues how what binds together the bugaboos of Talbot, Tenniel and the Georgian satirists ...
Baker, James
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Os sons das palavras: possibilidades e limites da novela gráfica

open access: yesEstudos de Literatura Brasileira Contemporânea, 2011
The graphic novel today aims to a literary status, but its attributes at the same time favor such possibility and frustate it. In this analysis, I demonstrate how time control by the artists is at the center of this process. Halting the reader, distract-
Elvira Vigna
doaj  

Interview with Leo Ortolani

open access: yesBetween, 2016
Intervista a Leo ...
Andrea Bernardelli, Marina Guglielmi
doaj   +1 more source

The Drawn-Out Battle Against Stigma: Mental Health in Modern American Comics and Graphic Novels [PDF]

open access: yes, 2012
The discussion of mental health issues in the media significantly shapes public perceptions, most notably in negative portrayals that contribute to the stereotyping of mental health patients.
Seah, Swee Khee Brenda
core   +1 more source

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