Results 91 to 100 of about 756 (154)

Characterization of the NFAT Gene Family in Grass Carp (Ctenopharyngodon idellus) and Functional Analysis of NFAT1 During GCRV Infection

Fishes
Nuclear factors of activated T cells (NFATs) are pivotal regulatory factors of immune responses, primarily by modulating T cell activity and regulating inflammatory cytokine gene transcription.
Yao Shen, Yitong Zhang, Chen Chen, Shitao Hu, Jia Liu, Yiling Zhang, Tiaoyi Xiao, Baohong Xu, Qiaolin Liu   +8 more
doaj   +1 more source

Genetic variations of body weight and GCRV resistance in a random mating population of grass carp [PDF]

, 2015
The grass carp (Ctenopharyngodon idellus) is an important species in freshwater aquaculture both in China and on a global scale. Variety degeneration and frequent diseases have limited the further development of grass carp aquaculture.
Li, Yongming, Huang, Rong, Wang, Yaping, Guo, Fuhua, Luo, Qing, Zhu, Zuoyan, Liao, Lanjie, He, Libo, Sun, Jiaxian   +8 more
core  

Comprehensive analysis of circRNA expression pattern and circRNA–mRNA–miRNA network in Ctenopharyngodon idellus kidney (CIK) cells after grass carp reovirus (GCRV) infection

Aquaculture, 2019
Abstract Grass carp reovirus (GCRV) causes grass carp hemorrhage disease and is one of the most damaging factors in the culture of grass carp (Ctenopharyngodon idellus). Until now, the mechanisms underlying GCRV infection have been largely unknown. To explore the molecular responses to GCRV infection in C.
Bo Liu, Rui Yuan, Zi Liang, Tingting Zhang, Min Zhu, Xing Zhang, Wei Geng, Ping Fang, Mengsheng Jiang, Zhangyan Wang, Yongjie Feng, Xunmeng Liu, Yang Zhou, Renyu Xue, Guangli Cao, Hui Chen, Xiaolong Hu, Chengliang Gong   +17 more
openaire   +2 more sources

Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication

iScience
Summary: Viral inclusion bodies (VIBs) are subcellular structures required for efficient viral replication. How type II grass carp reovirus (GCRV-II), the mainly prevalent strain, forms VIBs is unknown.
Chu Zhang, Hui Wu, Hao Feng, Yong-An Zhang, Jiagang Tu   +4 more
doaj   +1 more source

Characterizations of four toll-like receptor 4s in grass carp Ctenopharyngodon idellus and their response to grass carp reovirus infection and lipopolysaccharide stimulation [PDF]

, 2015
In this study, the subcellular localization, tissue distribution and response to grass carp reovirus (GCRV) infection and lipopolysaccharide (LPS) stimulation of four grass carp Ctenopharyngodon idellus toll-like receptor 4 (tlr4) genes were investigated.
Wang, Y. P., Liao, L. J., Huang, R., Zhu, Z. Y., Wang, YP (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China., Li, Y. M., Pei, Y. Y.   +6 more
core   +1 more source

The use of an in vitro microneutralization assay to evaluate the potential of recombinant VP5 protein as an antigen for vaccinating against Grass carp reovirus

Virology Journal, 2011
Background Grass carp reovirus (GCRV) is the causative pathogen of grass carp hemorrhagic disease, one of the major diseases damaging grass carp Ctenopharyngon idellus breeding industry in China.
Xu Dan, Yang Qian, Xu Hongxu, He Yongxing, Lu Liqun   +4 more
doaj   +1 more source

Comparison of the blood parameters and histopathology between grass carp infected with a virulent and avirulent isolates of genotype II grass carp reovirus [PDF]

, 2019
Grass carp hemorrhagic disease caused by grass carp reovirus (GCRV) is the most important disease for grass carp aquaculture. Its typical clinical symptom is haemorrhaging, although the mechanism was remained unclear.
Yin, Jiyuan, Wang, Yingying, Li, Yingying, Hu, Huzi, Wang, Chengbao, Gao, Caixia, Tang, Yafang, Bergmann, Sven, Wang, Qing, Zeng, Weiwei   +9 more
core   +1 more source

The destiny of the resistance/susceptibility against GCRV is controlled by epigenetic mechanisms in CIK cells

Scientific Reports, 2017
Hemorrhagic disease caused by grass carp reovirus (GCRV) has severely threatened the grass carp (Ctenopharyngodon idella) cultivation industry. It is noteworthy that the resistance against GCRV infection was reported to be inheritable, and identified at ...
Xueying Shang, Chunrong Yang, Quanyuan Wan, Youliang Rao, Jianguo Su   +4 more
doaj   +1 more source

APC receptor TLR22a-targeted antigen structure optimization enhances immune protection against grass carp reovirus II

Water Biology and Security
Grass carp (Ctenopharyngodon idella), a cornerstone of global freshwater aquaculture, face severe threats from grass carp reovirus II (GCRV-II), which causes massive mortality and economic losses.
Xue-Feng Wei, Zhu-Yang Deng, Fei-Fan Xu, Jia-Lun Tang, Le-Yang Chen, Bin Zhu   +5 more
doaj   +1 more source

Molecular Characterization and Antiviral Function Against GCRV of Complement Factor D in Barbel Chub (Squaliobarbus curriculus)

Fishes
The barbel chub (Squaliobarbus curriculus) exhibits remarkable resistance to grass carp reovirus (GCRV), a devastating pathogen in aquaculture. To reveal the molecular basis of this resistance, we investigated complement factor D (DF)—a rate-limiting ...
Yu Xiao, Zhao Lv, Yuling Wei, Mengyuan Zhang, Hong Yang, Chao Huang, Tiaoyi Xiao, Yilin Li   +7 more
doaj   +1 more source