Results 1 to 10 of about 11,467 (254)
New England Journal of Medicine, 2010 Graves' orbitopathy is part of an autoimmune systemic disease which compiles hyperthyroidism, orbitopathy, dermopathy and acropachy. Stimulating antibodies against the TSH receptor play the central pathogenetic role. Main symptoms of Graves' orbitopathy comprise soft tissue inflammation, proptosis impairment of ocular motility and lid retraction ...
A, Eckstein, J, Esser
exaly +8 more sources
New England Journal of Medicine, 2009 A 40-year-old woman who recently received a diagnosis of Graves' disease comes for a follow-up visit. She has been taking methimazole, at a dose of 10 mg daily, and is now euthyroid, but for the past 3 months, she has had bothersome eye symptoms ...
Bartalena, Luigi +1 more
core +3 more sources
Teprotumumab for Thyroid-Associated Ophthalmopathy [PDF]
New England Journal of Medicine, 2017 BACKGROUND: Thyroid-associated ophthalmopathy, a condition commonly associated with Graves’ disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns ...
Terry J Smith +2 more
exaly +3 more sources
Autophagy in graves’ ophthalmopathy [PDF]
Frontiers in Cell and Developmental Biology, 2023 Graves’ ophthalmopathy (GO) is an inflammatory autoimmune disease that affects the eyes. It can significantly alter the quality of life in patients because of its distinctive pathological appearance and the effect on vision.
Yu-Qing Chen +6 more
doaj +2 more sources
Increased percentage of L-selectin+ and ICAM-1+ peripheral blood CD4+/CD8+ T cells in active Graves' ophthalmopathy. [PDF]
Folia Histochemica et Cytobiologica, 2009 The purpose of the study was to evaluate the percentage of CD4+/CD8+ peripheral T cells expressing CD62L+ and CD54+ in patients with Graves' disease and to assess if these estimations could be helpful as markers of active ophthalmopathy.
Alina Bakunowicz-Lazarczyk +4 more
doaj +4 more sources
Treatment of Graves' ophthalmopathy
Клиническая и экспериментальная тиреоидология, 2010 Graves' ophthalmopathy is one of most frequent extrathyroid manifestation of autoimmune thyroid diseases. In 3–5% cases it has severe progress and requires specific therapy.
Anna Dalmatova, Elena Grineva
doaj +3 more sources
Graves’ ophthalmopathy: the clinical and psychosocial outcomes of different medical interventions – a systematic review [PDF]
BMJ Open OphthalmologyBackground Graves’ ophthalmopathy is a complex autoimmune disorder that can significantly affect quality of life (QoL), vision and physical appearance.
Maralyn Druce +2 more
doaj +2 more sources
Clinical Ophthalmology, 2015 Thayalini Shanmuganathan,1 Christian Girgis,2 Hooshang Lahooti,1 Bernard Champion,1 Jack R Wall1 1Department of Medicine, Nepean Clinical School, Nepean Hospital, The University of Sydney, Sydney, 2Department of Medicine, Westmead Millennium Institute ...
Shanmuganathan T +4 more
doaj +1 more source