Results 11 to 20 of about 11,467 (254)

An Appraisal of the Preventive Effect of Statins on the Development of Graves’ Ophthalmopathy: A Hospital-Based Cohort Study [PDF]

open access: yesOphthalmology and Therapy
Introduction Graves’ ophthalmopathy (GO) is an autoimmune inflammatory disorder observed in a substantial proportion of patients with Graves’ disease (GD), with debilitating symptoms of disfiguring, periorbital pain, dry eyes, diplopia, and even visual ...
Grace Chia-Yen Hsu   +4 more
doaj   +2 more sources

TSHR-Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition. [PDF]

open access: yesAdv Sci (Weinh)
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Zhang Y   +16 more
europepmc   +2 more sources

Graves' ophthalmopathy [PDF]

open access: yesSwiss Medical Weekly, 2002
Swiss Medical Weekly
doaj   +3 more sources

A Case of Thyrotoxic Periodic Paralysis and Graves’ Ophthalmopathy Patient in Coincidence with Chronic Hepatitis B Infection

open access: yesThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Graves' disease is an autoimmune thyroid disease with several characteristic symptoms and signs. Graves' ophthalmopathy, an inflammatory disease in the orbital area, is the main extrathyroid manifestation of Graves' disease.
Herry Krisnata Ginting, Soebagijo Adi
doaj   +1 more source

Overview of Graves Ophthalmopathy Literature From 1999 to 2019: Bibliometric Analysis

open access: yesInteractive Journal of Medical Research, 2021
BackgroundResearch on Graves ophthalmopathy has increased remarkably over the last 2 decades; however, few statistical analyses of the data presented in these publications have been conducted.
Jiamin Cao   +5 more
doaj   +1 more source

Graves' ophthalmopathy. [PDF]

open access: yesJournal of ophthalmic nursing & technology, 1990
Graves' disease is an inflammatory condition affecting the thyroid gland and the eye. The triad of exophthalmos, goiter, and hyperthyroidism is classic Graves' disease. Each of the signs may appear in an individual patient, although separated by weeks, months, or years.
R P, Yeatts, D M, Clontz
  +6 more sources

Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]

open access: yes, 2020
Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter   +7 more
core   +1 more source

Extraocular muscle sampled volume in Graves' orbitopathy using 3-T fast spin-echo MRI with iterative decomposition of water and fat sequences [PDF]

open access: yes, 2018
Background: Current magnetic resonance imaging (MRI) techniques for measuring extraocular muscle (EOM) volume enlargement are not ideally suited for routine follow-up of Graves’ ophthalmopathy (GO) because the difficulty of segmenting the muscles at ...
BRUSCOLINI, ALICE   +4 more
core   +1 more source

Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]

open access: yes, 1996
To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E.   +2 more
core   +1 more source

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