Results 51 to 60 of about 229,521 (146)
Evaluation of clinical features and risk factors in juvenile Graves' ophthalmopathy [PDF]
, 2016 [...]. Aim and objectives. The aim of the present study was to evaluate the features of juvenile Graves' ophthalmopathy and identify the risk factors that may influence the development of the disease. The objectives of the study were as follows: 1.
Jarušaitienė, Dalia
core
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Acta Ophthalmologica, Volume 104, Issue 1, Page e28-e38, February 2026.Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
The Influence of Prior Hyperthyroidism on Euthyroid Graves’ Ophthalmopathy [PDF]
, 2014 Background. To investigate the influence of previous exposure to elevated thyroid hormones in euthyroid Graves' ophthalmopathy. Design. Retrospective, observational case series in university setting Median follow-up of 1 year with ranges of 0,8-7,6 years.
Ilse Mombaerts +5 more
core +1 more source
Immunological Aspects of Graves’ Ophthalmopathy [PDF]
BioMed Research International, 2019 The body’s autoimmune process is involved in the development of Graves’ disease (GD), which is manifested by an overactive thyroid gland. In some patients, autoreactive inflammatory reactions contribute to the development of symptoms such as thyroid ophthalmopathy, and the subsequent signs and symptoms are derived from the expansion of orbital adipose ...
Łacheta, Dominika +8 more
openaire +2 more sources
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
A Case of Euthyroid Graves’ Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody
Case Reports in Endocrinology, 2018 We report of a case of Graves’ ophthalmopathy presented solely with symptoms of the eyes with normal thyroid function tests and negative immunoreactive TSH receptor autoantibody.
Asami Hotta +17 more
doaj +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.An Allosteric Strategy for Thyroid Eye Disease This illustration depicts an aptamer (purple) binding to the target protein (white) at an allosteric site. This strategic binding induces a conformational change that acts as a shield, preventing pathogenic autoantibodies (red) from initiating the disease cascade, while leaving the protein's normal ...
Yanchen Zhang +16 more
wiley +1 more source
Hypothyroid Graves’ Ophthalmopathy: Report of Two Cases
Endocrinology Research and Practice, 2007 Graves’ disease is an autoimmune disorder of the thyroid gland. Ophthalmopathy is the most common peripheral manifestation of Graves’ disease. It is a very rare condition that a Graves’ patient presents with spontaneous hypothyroidism.
Barış Akıncı +2 more
doaj +2 more sources
Progress in the pathogenesis of thyroid-associated ophthalmopathy and new drug development
Taiwan Journal of Ophthalmology, 2020 Thyroid-associated ophthalmopathy (TAO) is the most common extrathyroidal manifestation of toxic diffuse goiter (Graves' disease), also known as Graves' ophthalmopathy/orbitopathy. As an organ-specific autoimmune disease, the pathogenesis of TAO is still
Yazhuo Huang +3 more
doaj +1 more source
A Pruritic Predicament: An Unusual Presentation of Graves’ Disease Complicated by Pregnancy
Case Reports in Medicine, Volume 2026, Issue 1, 2026.Pruritus is a known but uncommon symptom of hyperthyroidism that can be misinterpreted or overlooked in a patient presentation. This is a case report of a 40‐year‐old female who presents with a 3‐month history of severe, worsening pruritus. Further history demonstrated potential signs of hyperthyroidism, and laboratory values demonstrated low TSH ...
Rob Lawless +4 more
wiley +1 more source