Results 61 to 70 of about 225,386 (188)
International Journal of Endocrinology, Volume 2026, Issue 1, 2026.Background Xiehuo Pingtu San (XHPTS) has been shown to be safe and effective in treating thyroid eye disease (TED), yet its underlying mechanisms remain unclear. This study aimed to elucidate the active ingredients of XHPTS and their therapeutic mechanisms in TED through network pharmacology, molecular docking, and molecular dynamics simulations ...
Ping Wang +6 more
wiley +1 more source
International Journal of Endocrinology, Volume 2026, Issue 1, 2026.Background Thyroid eye disease (TED) is an autoimmune inflammatory condition linked to thyroid dysfunction, which can result in disfigurement and potential vision loss. Recently, immunomodulatory therapies such as rituximab have demonstrated potential benefit in managing TED.
Ming Lu +3 more
wiley +1 more source
Journal of Ophthalmology, Volume 2026, Issue 1, 2026.Purpose The conversion rate of ocular myasthenia gravis (OMG) to generalized myasthenia gravis (GMG) lacks definitive predictors. Methods This retrospective cohort study analyzed data collected at Siriraj Hospital between January 2007 and December 2019 to identify factors influencing OMG generalization and the time to conversion. The records of 200 OMG
Wanicha Chuenkongkaew +7 more
wiley +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng +14 more
wiley +1 more source
Clinical Presentation of Graves’ Ophthalmopathy
Ophthalmic Research, 2009 The eye findings of Graves’ ophthalmopathy were prospectively recorded in 90 consecutive untreated patients (66 females, 24 males; mean age 44.5 years) according to the 1977 NOSPECS classification. Soft-tissue involvement was observed in 90%, proptosis ≥ 23 mm in 30%, eye muscle involvement in 60%, corneal involvement in 9% and sight loss in 34%.
Wiersinga, W. M. +4 more
openaire +3 more sources
Thyroid-associated Ophthalmopathy
, 2017 Thyroid-associated ophthalmopathy is the most frequent extrathyroidal involvement of Graves’ disease but it sometimes occurs in euthyroid or hypothyroid patients.
Kaan Gündüz, Esra Şahlı
core +1 more source
Journal of Patient-Reported Outcomes, 2019 Purpose To develop and assess the psychometric properties of the Thai version of the Graves’ Ophthalmopathy Quality of Life (GO-QOL) questionnaire. Background Graves’ ophthalmopathy (GO) is a chronic condition that causes negative self-image and impaired
Mingkwan Lumyongsatien +8 more
doaj +1 more source
Orbital gallium-67 scintigraphy in Graves' ophthalmopathy
, 2002 Assessment of orbital disease activity in patients with Graves' ophthalmopathy is important in planning the therapeutic approach. In this study, orbital uptake of gallium-67 citrate (Ga-67) was evaluated in 46 consecutive patients demonstrating active or
Arslan, M +7 more
core +1 more source
Endoscopic orbital decompression in Graves ophthalmopathy - Case report
, 2018 Graves ophthalmopathy, an autoimmune disease, associated with hypermetabolism, enlargement of the thyroid gland and exophthalmia are the most frequent expressions of Graves’ disease, which often require surgical treatment.
Tatiana Decuseara +5 more
core +1 more source
Folia Histochemica et Cytobiologica, 2009 The purpose of the study was to evaluate the percentage of CD4+/CD8+ peripheral T cells expressing CD62L+ and CD54+ in patients with Graves' disease and to assess if these estimations could be helpful as markers of active ophthalmopathy.
Alina Bakunowicz-Lazarczyk +4 more
doaj +1 more source