Pulse methylprednisolone therapy is the recommended therapy for moderate to severe and active ophthalmopathy, but high dose pulse methylprednisolone therapy is marred by the chances of fulminant hepatic failure and the high cost of therapy. Dexamethasone
Rajeev Philip +5 more
doaj +1 more source
Miosite do músculo reto medial como forma atípica de apresentação de linfoma tipo MALT: relato de caso [PDF]
Here we describe the rare case of a 55-year-old man with medial rectus muscle myositis as an atypical presentation of non-Hodgkin B-cell mucosa-associated lymphoma (MALT).
Dittrich, Mirtha Alicia Ramirez +4 more
core +4 more sources
Glymphatic System Dysfunction in Thyroid‐Associated Ophthalmopathy: A Multimodal MRI Study
TAO patients exhibit impaired glymphatic function, with reduced DTI‐ALPS indices and gBOLD‐CSF coupling, but unchanged choroid plexus volume. These alterations correlate with neuropsychological symptoms and sleep disturbances. Restoring glymphatic activity may offer a therapeutic approach to enhance patient outcomes.
Lijie Zhang +4 more
wiley +1 more source
Clinical evaluation of Graves ophthalmopathy [PDF]
Introduction. Graves ophthalmopathy is an autoimmune disease, which is the consequence of thyroid dysfunction. Ocular manifestations occur in 50% of patients with Graves disease.
Janićijević-Petrović Mirjana A. +5 more
doaj +1 more source
Selenium improves mild Graves’Orbitopathy: a randomized, double-blind, placebo-controlled study. [PDF]
Background Free oxygen radicals and cytokines play a pathogenic role in Graves’ orbitopathy (GO). This study reports the results of a randomized, double-blind, placebo-controlled trial on the effect of selenium, an antioxidant agent, or pentoxifylline ...
ALTEA, MARIA ANTONIETTA
core
Building the case for insulin-like growth factor receptor-I involvement in thyroid-associated ophthalmopathy [PDF]
The pathogenesis of orbital Graves' disease (GD), a process known as thyroid-associated ophthalmopathy (TAO), remains incompletely understood. The thyrotropin receptor (TSHR) represents the central autoantigen involved in GD and has been proposed as the ...
Janssen, J.A.M.J.L. (Joop) +1 more
core +4 more sources
Corneal Confocal Microscopy to Diagnose Peripheral Neuropathy: A Systematic Review and Meta‐Analysis
ABSTRACT Background and Objectives Peripheral neuropathy (PN) may be diagnosed late or may remain undiagnosed. Studies have shown that measurement of corneal nerve fiber length (CNFL) using corneal confocal microscopy (CCM) may have diagnostic utility in diabetic and other peripheral neuropathies. Methods The main databases [CENTRAL, Embase (Ovid), and
Ioannis N. Petropoulos +6 more
wiley +1 more source
Association between copy number variation of complement component C4 and Graves' disease [PDF]
Background Gene copy number of complement component C4, which varies among individuals, may determine the intrinsic strength of the classical complement pathway.
Yu-Huei Liu +7 more
core +2 more sources
Double Filtration Plasmapheresis for Thyroid Storm With Encephalopathy: A Case Report
ABSTRACT Thyroid storm is a life‐threatening endocrine emergency with a mortality rate of up to 17%. Standard treatment includes antithyroid drugs (ATD), β‐blockers, and glucocorticoids. However, some patients may require blood purification therapies, such as plasmapheresis, due to the ineffectiveness of standard treatments or contraindications like ...
Qisheng Lin +5 more
wiley +1 more source
Active Moderate-to-Severe Graves' Orbitopathy in a Patient With Type 2 Diabetes Mellitus and Vascular Complications [PDF]
Background: Graves’ orbitopathy (GO) is the main extrathyroidal manifestation of Graves’ disease (GD). Diabetes mellitus (DM) has been reported to be a risk factor in patients with GO.
Biondi, B +5 more
core +2 more sources

