Results 41 to 50 of about 268,622 (261)

Computed tomography for diagnosing Graves ophtalmopathy [PDF]

open access: yesRomanian Medical Journal, 2021
Graves ophtalmopathy (GO), thyroid eye disease (TED) and thyroid - associated orbitopathy (TAO) are terms referring to an autoimmune inflammatory process that affects the adipogenesis of orbital fat and periorbital tissue, associated with dysthyroidism ...
Mihai Leonard C. Grecescu
doaj   +1 more source

Dysthyroid optic neuropathy: update on pathogenesis, diagnosis, and management [PDF]

open access: yes, 2017
INTRODUCTION: Dysthyroid optic neuropathy (DON) is a severe manifestation of thyroid eye disease (TED) that can result in permanent vision loss. Management is complex, multidisciplinary, and involves medical and/or surgical therapies.
Blandford, Alexander D.   +3 more
core   +1 more source

TSH receptor specific monoclonal autoantibody K1‐70TM targeting of the TSH receptor in subjects with Graves' disease and Graves' orbitopathy—Results from a phase I clinical trial

open access: yesClinical Endocrinology, 2022
In Graves' disease (GD), autoantibodies to the thyroid stimulating hormone receptor (TSHR) cause hyperthyroidism. The condition is often associated with eye signs including proptosis, oedema, and diplopia (collectively termed Graves' orbitopathy [GO ...
J. Furmaniak   +4 more
semanticscholar   +1 more source

The thyroid, the eyes and the gut: a possible connection [PDF]

open access: yes, 2017
Graves’ disease (GD) is an autoimmune disorder responsible for 60–90% of thyrotoxicosis, with an incidence of 1 to 2 cases per 1000 population per year in England.
Covelli, D., Ludgate, Marian Elizabeth
core   +2 more sources

Exophthalmos in a young woman with no Graves’ disease – a case report of IgG4-related orbitopathy

open access: yesBMC Ophthalmology, 2018
Background Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy ...
Annamaria Erdei   +4 more
doaj   +1 more source

Thyroid Eye Disease due to Immune Reconstitution Inflammatory Syndrome as a Consequence of Antiretroviral Therapy in the Setting of AIDS

open access: yesCase Reports in Endocrinology, 2020
We describe a case of worsening Graves’ orbitopathy due to immune reconstitution inflammatory syndrome (IRIS) in a 38-year-old HIV-infected male after beginning ART (antiretroviral therapy).
Ravali Nallu   +3 more
doaj   +1 more source

Orbital lymphoma associated with Graves’ disease: A case report [PDF]

open access: yesVojnosanitetski Pregled, 2014
Introduction. The presence of bilateral exophthalmos and palpebral, periorbital edema associated with hyperthyroidism is most often considered as an initial sign of Graves’ ophthalmopathy.
Hajduković Zoran   +4 more
doaj   +1 more source

Sirolimus as a second-line treatment for Graves’ orbitopathy

open access: yesJournal of Endocrinological Investigation, 2022
A beneficial effect of sirolimus in Graves’ orbitopathy (GO) was reported, suggesting a possible use in clinical practice. We conducted an observational, single-centre, no-profit, clinical study to investigate the efficacy of sirolimus as a second-line ...
G. Lanzolla   +8 more
semanticscholar   +1 more source

The change in the clinical presentation of Graves’ disease: a 30 years retrospective survey in an academic Brazilian tertiary center

open access: yesArchives of Endocrinology and Metabolism, 2020
Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto   +4 more
doaj   +1 more source

Graves' ophthalmopathy [PDF]

open access: yes, 2009
A 40-year-old woman who recently received a diagnosis of Graves' disease comes for a follow-up visit. She has been taking methimazole, at a dose of 10 mg daily, and is now euthyroid, but for the past 3 months, she has had bothersome eye symptoms ...
Bartalena, Luigi   +1 more
core   +1 more source

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