Results 11 to 20 of about 4,646 (173)
Autophagy in graves’ ophthalmopathy [PDF]
Frontiers in Cell and Developmental Biology, 2023 Graves’ ophthalmopathy (GO) is an inflammatory autoimmune disease that affects the eyes. It can significantly alter the quality of life in patients because of its distinctive pathological appearance and the effect on vision.
Yu-Qing Chen +6 more
doaj +4 more sources
New England Journal of Medicine, 2010 Graves' orbitopathy is part of an autoimmune systemic disease which compiles hyperthyroidism, orbitopathy, dermopathy and acropachy. Stimulating antibodies against the TSH receptor play the central pathogenetic role. Main symptoms of Graves' orbitopathy comprise soft tissue inflammation, proptosis impairment of ocular motility and lid retraction ...
Rebecca S Bahn, Bahn Rebecca S
exaly +7 more sources
Quantitative MRI Assessment of Orbital Structures in Radioactive Iodine-131 Therapy for Inactive Graves' Ophthalmopathy. [PDF]
Int J EndocrinolObjective The understanding regarding the role of orbital magnetic resonance imaging (MRI) in predicting the prognosis of radioactive iodine‐131 (I‐131) therapy for patients with inactive Graves’ ophthalmopathy (GO) is limited. Therefore, this study aimed to explore the application of MRI quantitative measurements of orbital structures in radioactive I‐
Wang M, Shen ZY, Wu XW.
europepmc +2 more sources
TSHR-Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition. [PDF]
Adv Sci (Weinh)This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Zhang Y +16 more
europepmc +2 more sources
Graves’ ophthalmopathy: the clinical and psychosocial outcomes of different medical interventions – a systematic review [PDF]
BMJ Open OphthalmologyBackground Graves’ ophthalmopathy is a complex autoimmune disorder that can significantly affect quality of life (QoL), vision and physical appearance.
Maralyn Druce +2 more
doaj +2 more sources
Clinical evaluation of Graves ophthalmopathy [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2012 Introduction. Graves ophthalmopathy is an autoimmune disease, which is the consequence of thyroid dysfunction. Ocular manifestations occur in 50% of patients with Graves disease.
Janićijević-Petrović Mirjana A. +5 more
doaj +4 more sources
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022 Graves' disease is an autoimmune thyroid disease with several characteristic symptoms and signs. Graves' ophthalmopathy, an inflammatory disease in the orbital area, is the main extrathyroid manifestation of Graves' disease.
Herry Krisnata Ginting, Soebagijo Adi
doaj +1 more source
Overview of Graves Ophthalmopathy Literature From 1999 to 2019: Bibliometric Analysis
Interactive Journal of Medical Research, 2021 BackgroundResearch on Graves ophthalmopathy has increased remarkably over the last 2 decades; however, few statistical analyses of the data presented in these publications have been conducted.
Jiamin Cao +5 more
doaj +1 more source
Endocrinology Research and Practice, 2022 In this study, we investigated Thyrotropin Receptor Antibody (TRab) levels in Hashimoto and Graves' diseases. A total of 189 patients and 25 controls were assessed, retrospectively.
Demet Çorapçıoğlu +8 more
doaj +2 more sources
Prognostic indicators for the development of strabismus among patients with graves’ ophthalmopathy
Journal of Clinical & Translational Endocrinology, 2017 Objective: Thyroid eye disease (TED), an autoimmune inflammatory process involving the orbital tissues around the eye, is the most common extra-thyroidal manifestation of Graves’ disease (GD). Due to changes in the patient’s appearance, TED is a socially
Tiffany Y. Lin +4 more
doaj +1 more source