Results 21 to 30 of about 4,959 (174)

Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts–a possible explanation of the link between smoking and Graves’ ophthalmopathy

open access: yesInternational Journal of Ophthalmology, 2014
AIM: To assess the effects of hypoxia on human orbital fibroblasts (OF) on adipogenesis and adipocytokine production.METHODS:Human OF were derived from tissues obtained from patients with Graves’ ophthalmopathy (GO) and from patients without known ...
Chiaw Ling Chng   +6 more
doaj   +1 more source

Extraocular muscle repositioning as the last therapeutic option for a patient with a severe course of Graves’ Ophthalmopathy: a case report

open access: yesBMC Ophthalmology, 2018
Background Graves’ disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves’ Ophthalmopathy.
Andrea Rau   +4 more
doaj   +1 more source

Dose‐Dependent Efficacy of Radioiodine Therapy in Pediatric Graves’ Disease: A Retrospective Study of Hypothyroidism Risk and the Predictive Role of Thyroid Hormone Parameters

open access: yesiRADIOLOGY, Volume 4, Issue 5, Page 385-392, October 2026.
RAI therapy demonstrated time‐dependent efficacy in pediatric Graves' disease, with gradually increasing treatment success and hypothyroidism incidence during follow‐up. Higher planned activity (≥ 0.15 mCi/g) was associated with a higher successful rate than lower planned activity (< 0.15 mCi/g), and LASSO analysis identified FT3 and TSH as candidate ...
Xiaoxue Tian   +8 more
wiley   +1 more source

Graves’ ophthalmopathy – thyroid eye disease

open access: yesJournal of Education, Health and Sport, 2019
Graves’ disease (GD) is an autoimmune disorder that affects thyroid. It is caused by antibody, named thyroid-stimulating immunoglobulin (TIS) that acts like thyroid stimulating hormone (TSH), resulting in thyroid hormone overproduction – condition called
Dagna Siedlecka   +3 more
doaj   +3 more sources

Novel observational study protocol to develop a prediction model that identifies patients with Graves’ ophthalmopathy insensitive to intravenous glucocorticoids pulse therapy

open access: yesBMJ Open, 2021
Introduction Intravenous glucocorticoids pulse therapy is the first-line treatment for moderate-to-severe and active Graves’ ophthalmopathy, with a large proportion of patients having poor efficacy and exposed to the risk of glucocorticoids adverse ...
Jing Sun   +4 more
doaj   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang   +10 more
wiley   +1 more source

World thyroidology news

open access: yesКлиническая и экспериментальная тиреоидология, 2014
The article is to overview papers: Effect of vitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis. Management of neonates born to women with Graves’ disease: a cohort study.
Yuliya Aleksandrovna Manuylova   +1 more
doaj   +1 more source

Bilateral IgG4‐Related Dacryoadenitis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Chronic dacryoadenitis is an uncommon inflammation of the lacrimal gland that may have various etiologies with similar presentations. IgG4‐related ophthalmic disease most often manifests as painless lacrimal gland enlargement, so the clinicians should consider IgG4‐related disease as a diagnostic possibility for dacryoadenitis.
Yan Song, Lin Ding, Tao Shen
wiley   +1 more source

Graves' Disease Presenting as Refractory Panic Attacks: Diagnostic Clarification Through Thyroid Scintigraphy

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Graves' disease may rarely present with predominant neuropsychiatric symptoms, such as severe, treatment‐resistant panic attacks, leading to misdiagnosis as a primary psychiatric disorder. We describe a 30‐year‐old woman with refractory panic attacks and night terrors who was initially treated with anxiolytics and antidepressants.
Mahsa Satari Gholami
wiley   +1 more source

Evaluation of Galectin-3 in Graves’ Disease With and Without Ophthalmopathy

open access: yesEndocrinology Research and Practice, 2023
Objective: There is a link between thyroid-associated ophthalmopathy and Graves’ disease; however, the exact pathophysiological mechanism remains unclear.
Muhammed Akın   +4 more
doaj  

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