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Treatment of Graves' ophthalmopathy
Graves' ophthalmopathy is one of most frequent extrathyroid manifestation of autoimmune thyroid diseases. In 3–5% cases it has severe progress and requires specific therapy.
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Epidemiology and prevention of Graves' ophthalmopathy
Graves' ophthalmopathy is clinically relevant in approximately 50% of patients with Graves' disease, severe forms affecting 3%-5% of patients. Two age peaks of incidence are observed in the fifth and seventh decades of life, with slight differences ...
Wiersinga, Wilmar M. +2 more
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Update on the medical treatment of Graves’ ophthalmopathy
Gregory J Griepentrog, James A GarrityDepartment of Ophthalmology, Mayo Clinic, Rochester, MN, USAPurpose: To review recent advances in the understanding of Graves’ ophthalmopathy (GO) pathogenesis as well as discuss current and future medical ...
Gregory J Griepentrog, James A Garrity
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Tom McCorquodale,1 Hooshang Lahooti,1 Bamini Gopinath,2 Jack R Wall11Department of Medicine, Nepean Clinical School, the University of Sydney, Penrith, NSW, Australia; 2Centre for Vision Research, the University of Sydney, Westmead Hospital, Westmead ...
McCorquodale T +3 more
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A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Sarkar, Gobinda +4 more
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Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Wenzel, Björn E. +2 more
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The Efficiacy of High Dose Pulse Steroid (Methylprednisolone) Therapy in Graves Ophthalmopathy
Thyroid ophthalmopathy is the most common cause of bilateral or unilateral proptosis in adults. Since the recognition of autoimmune mechanisms in the pathogenesis of Graves' ophthalmopathy, a number of investigators have reported on the use of various ...
Bilgin Özmen, Esin Erkin, Murat Saruç
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Ophthalmopathy Consciousness Level in Graves Patients: Graves Ophthalmopathy
Objective: We aimed to examine the knowledge and consciousness levels of participators about Graves orbitopathy (GO) by conducting an investigation of ophthalmopathy consciousness of Graves patients, providing coordination among all health insti- tutions and ophthalmologists and giving information about the subject to patients. Materials and Methods: A
Kan E.K. +4 more
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The thickness of the retrobulbar portion of the optic nerve in Graves ophthalmopathy measured by ultrasound [PDF]
Introduction. The clinical diagnostic of Graves ophthalmopathy is based on the association of ocular signs and the disease of the thyroid gland. The evolution of the disease involves the development of eye globe protrusion, extraocular muscle thickening ...
Stefanović Ivan +3 more
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Relatam-se dois casos clínicos de prolapso de gordura orbitária, sendo um associado à oftalmopatia de Graves. Os pacientes apresentavam em comum exame clínico com elevação na região temporal da órbita direita e aumento da gordura intraorbitária na ...
Kim-Ir-Sen Santos Teixeira +4 more
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