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Immunological Aspects of Graves’ Ophthalmopathy
BioMed Research International, 2019 The body's autoimmune process is involved in the development of Graves' disease (GD), which is manifested by an overactive thyroid gland. In some patients, autoreactive inflammatory reactions contribute to the development of symptoms such as thyroid ...
Alicja Głuszko +2 more
exaly +2 more sources
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Medical Clinics of North America, 1995
Graves' ophthalmopathy is an organ-specific autoimmune process strongly linked to Graves' hyperthyroidism. Although the hyperthyroidism can be successfully treated, it is often the ophthalmopathy that produces the greatest long-term disability for patients suffering from this disease.
V. Fatourechi +2 more
openaire +3 more sources
Graves' ophthalmopathy is an organ-specific autoimmune process strongly linked to Graves' hyperthyroidism. Although the hyperthyroidism can be successfully treated, it is often the ophthalmopathy that produces the greatest long-term disability for patients suffering from this disease.
V. Fatourechi +2 more
openaire +3 more sources
Klinische Monatsblätter für Augenheilkunde, 2021
Purpose The study was conducted for the assessment of the retinal nerve fiber layer, ganglion cell layer, and subfoveal choroidal thickness changes in patients with inactive Gravesʼ ophthalmopathy (GO) using swept-source optical coherence tomography (SS ...
M. Kurt +4 more
semanticscholar +1 more source
Purpose The study was conducted for the assessment of the retinal nerve fiber layer, ganglion cell layer, and subfoveal choroidal thickness changes in patients with inactive Gravesʼ ophthalmopathy (GO) using swept-source optical coherence tomography (SS ...
M. Kurt +4 more
semanticscholar +1 more source
TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis
Journal of Clinical Endocrinology and Metabolism, 2016 Christine C Krieger +2 more
exaly +2 more sources
Low signal intensities of MRI T1 mapping predict refractory diplopia in Graves’ ophthalmopathy
Clinical Endocrinology, 2020In Graves’ ophthalmopathy (GO), fibrosis in extraocular muscles (EOMs) may be related to intravenous glucocorticoid (ivGC)‐resistant diplopia. Signal intensity (SI) of magnetic resonance imaging (MRI) T1 mapping can quantify properties of EOM components,
K. Matsuzawa +11 more
semanticscholar +1 more source
Inducing Graves’ ophthalmopathy
Journal of Endocrinological Investigation, 2004The majority of patients with Graves' disease (GD) have some degree of ocular involvement and this requires surgical or medical intervention in about 5% of cases. There are autoimmune and inflammatory processes operating in Graves' ophthalmopathy (GO), which together induce glycosaminoglycan production, edema and adipogenesis resulting in an increase ...
M, Ludgate, G, Baker
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Current Opinion in Ophthalmology, 2001
Graves ophthalmopathy (GO) is an autoimmune disease that typically affects the thyroid gland and the orbit. The roles of the thyroid stimulating hormone receptor and cellular and humoral immunity in the pathogenesis of GO are being investigated. Investigators are gaining insights into the epidemiology of GO as it relates to other ocular and autoimmune ...
openaire +3 more sources
Graves ophthalmopathy (GO) is an autoimmune disease that typically affects the thyroid gland and the orbit. The roles of the thyroid stimulating hormone receptor and cellular and humoral immunity in the pathogenesis of GO are being investigated. Investigators are gaining insights into the epidemiology of GO as it relates to other ocular and autoimmune ...
openaire +3 more sources
IMMUNOGENETICS OF GRAVES' OPHTHALMOPATHY
Clinical Endocrinology, 1988SUMMARYWe have performed an immunogenetic analysis of 53 patients with severe Graves' ophthalmopathy, 51 patients with Graves' disease but little or no clinically apparent eye disease, and 90 controls. The distribution of restriction fragment length polymorphisms was analysed in the three groups, using probes for the HLA‐DQα and DRβ regions, the T‐cell
A P, Weetman +5 more
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Journal of Cellular Biochemistry, 2019
The objective of this study was to study the levels of interleukin (IL)‐15 and IL‐17 in tears and orbital tissues of the patients with the Graves ophthalmopathy (GO) (active and inactive stages) and in controls.
Qun Chen
semanticscholar +1 more source
The objective of this study was to study the levels of interleukin (IL)‐15 and IL‐17 in tears and orbital tissues of the patients with the Graves ophthalmopathy (GO) (active and inactive stages) and in controls.
Qun Chen
semanticscholar +1 more source