Results 171 to 180 of about 18,853 (240)

Slight Water Loss Combined with Methyl Jasmonate Treatment Improves <i>Actinidia arguta</i> Resistance to Gray Mold by Modulating Reactive Oxygen Species and Phenylpropanoid Metabolism. [PDF]

Foods
Liu X, Wang Q, Wang F, Wei B, Zhou Q, Cheng S, Sun Y.   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Electroactive microneedle augmented stem cell therapy in myocardial infarction. [PDF]

Sci Adv
Zhang W, Shen Y, Jia S, Chen Y, Cai R, Jiao Y, Han Q, You J, Wang S, Wan X, Yu J, Gu Z, Gu Z, Zhang Y.   +13 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Extraction optimization of antifungal from Momordica charantia seeds against green mold disease in mushroom cultivation

International Journal of Applied Science and Engineering
Muhamad Ikmal Sirozi, Noor Hasyierah Mohd Salleh, Zarina Zakaria, Norhidayah Abd Aziz, Siti Aminah Hassan, Mohd Amin Zainal Abidin   +5 more
openaire   +1 more source

A Hypoxia-reoxygenation Injury Model in Self-assembling Human Cardioids. [PDF]

J Vis Exp
Parker LE, Thomas MC, Williams AB, Weirnick R, Ogliari AS, Karpurapu A, Barreto C, Manepalli S, Peña KC, Brandt AN, Booth M, Dalal NA, Lou F, Beard AJ, Karra R.   +14 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Nanogroove-Induced Enhancement of Neural Spike Activity in Stem Cell-Derived Networks. [PDF]

Micromachines (Basel)
Sabahi-Kaviani R, Shiryaeva MA, Luttge R.   +2 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Green Oil-in-Water Nanoemulsions for Delivery of Phytochemicals With Pesticidal Activity for Sustainable Food Production and Safety. [PDF]

Compr Rev Food Sci Food Saf
de Carvalho APA, Weitz DA, Conte-Junior CA.   +2 more
europepmc   +1 more source