Results 71 to 80 of about 292,880 (305)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Factors Influencing Online Purchase Intention: Evidence From Vegan Skincare Industry in Indonesia [PDF]

BIO Web of Conferences
This study examines the factors influencing green purchase intention in the context of vegan skincare. Furthermore, this study investigates how green products, green brand image, green price, and green promotion influence green purchase intention.
Aini Khofia Nida, Aini Nurul
doaj   +1 more source

Determinants of green purchase intention in Nigeria: The mediating role of green perceived value [PDF]

, 2015
The purpose of this paper is to examine the factors which may influence green behaviour in Nigeria.The study explores the influence of green price sensitivity, perceived behavioural control, green trust, government regulations, perceived green knowledge ...
Karatu, Victoria Masi Haruna, Nik Mat, Nik Kamariah   +1 more
core  

Green competence framework: Evidence from China [PDF]

, 2015
© 2015 Taylor & Francis Recently human resources management functions such as recruitment, selection, training and performance evaluation are expected in considering environmental management issues.
Albayrak T., Bhalla G., Gan C., Gendall P., Grunert S. C., Jackson S. E., Kaufmann H. R., Kim Y., Lin Wu, Muhammad D. Abdulrahman, Nachiappan Subramanian, Prithwiraj Nath, Renwick D., Schwartz J., Srinivasan A., Sun J., Sweetman P., Tan B. C., Tan B. C., Tan B. C.   +19 more
core   +4 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Does Green-Label Influence Green Purchase Intention, Attitude, Subjective Norms, Behavioral Control, and Willingness To Pay as Moderation?

International Research Journal of Business Studies
The purpose of this study was to test and analyze influenced eco-labels, attitudes, subjective norms, and behavioral control on green purchase intention, as well as willingness to pay as a mediator to strengthen the influence green purchase intention ...
Wisnu Ridho Lukmawan, Ririn Wulandari
doaj   +1 more source

The effects of label design characteristics on perceptions of genetically modified food [PDF]

, 2012
Objective. To explore the effects on perceptions of labelling food for genetically modified content. Background: there is increasing public pressure for the compulsory labelling of genetically modified food content on all food products, and yet little is
Coulson, N, Edworthy, J, Griffin, J, Hellier, E, Newbold, L, Tucker, M   +5 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Framing descriptive norms as self-benefit versus environmental benefit : self-construal’s moderating impact in promoting smart energy devices [PDF]

, 2019
Recently, awareness has been raised concerning the importance of sustainable energy use. Nevertheless, many obstacles must be overcome to change individuals’ energy consumption habits.
Cauberghe, Veroline, Hudders, Liselot, Mingolla, Carla   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source