Results 41 to 50 of about 854,773 (255)
A geometric attractor mechanism for self-organization of entorhinal grid modules
eLife, 2019 Grid cells in the medial entorhinal cortex (MEC) respond when an animal occupies a periodic lattice of ‘grid fields’ in the environment. The grids are organized in modules with spatial periods, or scales, clustered around discrete values separated on ...
Louis Kang, Vijay Balasubramanian
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A principle of economy predicts the functional architecture of grid cells
eLife, 2015 Grid cells in the brain respond when an animal occupies a periodic lattice of ‘grid fields’ during navigation. Grids are organized in modules with different periodicity.
Xue-Xin Wei +2 more
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On the optimality of grid cells
CoRR, 2016 Grid cells, discovered more than a decade ago [5], are neurons in the brain of mammals that fire when the animal is located near certain specific points in its familiar terrain. Intriguingly, these points form, for a single cell, a two-dimensional triangular grid, not unlike our Figure 3.
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Identifying Core Regions for Path Integration on Medial Entorhinal Cortex of Hippocampal Formation
Brain Sciences, 2020 Path integration is one of the functions that support the self-localization ability of animals. Path integration outputs position information after an animal’s movement when initial-position and movement information is input.
Ayako Fukawa +3 more
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To be a Grid Cell: Shuffling procedures for determining “Gridness” [PDF]
, 2017 Abstract Grid cells in freely behaving mammals are defined by the strikingly regular periodic spatial distribution of their firing. The standard method of identification calculates the “Gridness” of the spatial firing pattern, with significance being defined relative to the 95 th ...
Barry, C., Burgess, N.
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
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Hippocampal Remapping and Its Entorhinal Origin
Frontiers in Behavioral Neuroscience, 2018 The activity of hippocampal cell ensembles is an accurate predictor of the position of an animal in its surrounding space. One key property of hippocampal cell ensembles is their ability to change in response to alterations in the surrounding environment,
Patrick Latuske +3 more
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A new direction for grid cells [PDF]
Learning & Behavior, 2015 Krupic, Bauza, Burton, Barry, & O'Keefe (Grid cell symmetry is shaped by environmental geometry. Nature, 518, 232-235, 2015) found that the grids of grid cells in the entorhinal cortex of rats become sparser at the sharp end of a trapezoidal space. This makes grids, and grid cells, unsuitable for measuring distance traveled (odometry) and suggests that
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
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Grid cells: the missing link in understanding Parkinson’s disease?
Frontiers in NeuroscienceThe mechanisms underlying Parkinson’s disease (PD) are complex and not fully understood, and the box-and-arrow model among other current models present significant challenges. This paper explores the potential role of the allocentric brain and especially
Alexander Reinshagen
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