Results 241 to 250 of about 44,236 (298)

A CURE for synthetic regulation of gene expression: rapid screening of guide RNA efficacy as a framework for enabling undergraduate research in plant synthetic biology. [PDF]

Synth Biol (Oxf)
Bull T, Carlsen L, Hoglund N, Blarr J, Ciernia M, Daughtrey H, Gulnac K, Kathan Z, Labovitz B, Lonergan R, McDermott M, Medina A, Mikol Z, Miller Z, Prahl K, Rifai C, Schrems E, Shinkawa F, Summerfield J, Thevarajah E, Wagner S, Zimmerman T, Khakhar A.   +22 more
europepmc   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Stepwise Evaluation of Plasmid- and Adeno-Associated Virus-Based Knock-In Using A Triple-Reporter Platform. [PDF]

Genes Cells
Hara H, Uosaki H, Nakahara F, Inoue M, Hanazono Y.   +4 more
europepmc   +1 more source

Differential expression of TKS4 isoforms and their role in cellular processes in breast cancer

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
TKS4 isoforms are differentially expressed across human cell lines. TKS4L interacts with six novel SRC homology 3‐containing proteins, whereas no interactions were detected for TKS4b. SRC‐mediated phosphorylation promotes interactions of TKS4 with SH2 domains.
Serhii Kropyvko, Nazar Shevchuk, Olga Gubar, Kyrylo Lavrynenko, Yaroslav Nemesh, Denys Kozakov, Valentyn Polishchuk, Valentyna Kryklyva, Liubov Syvak, Nataliia Verovkina, Tetyana Gryaznova   +10 more
wiley   +1 more source

Rational Targeting and gRNA Design for Enhancing Quorum Quenching in <i>Pseudomonas aeruginosa</i> PAO1. [PDF]

Comput Struct Biotechnol J
Delgado-Nungaray JA, Figueroa-Yáñez LJ, Reynaga-Delgado E, García-Ramírez MA, Gonzalez-Reynoso O.   +4 more
europepmc   +1 more source

Critical role of cellular communication network factor 1 in early osteogenesis of mesenchymal stem cells primed by low‐intensity pulsed ultrasound and bone morphogenetic protein 2

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Cooperative stimulation of mechanical stress and osteoinductive factor, such as BMP‐2, enhances BMP signaling via the upregulation of BMP receptors. As a result, CCN1 production is increased and is secreted to the extracellular environment. Secreted CCN1 promotes Runx2 expression through interaction with integrin, leading to early osteogenic ...
Hsu Myat Paing, Satoshi Kubota, Masaharu Takigawa, Takuo Kuboki, Takashi Nishida   +4 more
wiley   +1 more source

Tuning mitotic recombination with patterned DNA nicks for precision mosaic analysis. [PDF]

Proc Natl Acad Sci U S A
Shen Y, Yeung AT, Wang B, Yeh CT, Ditchfield P, Korn E, Han C.   +6 more
europepmc   +1 more source

Protoplasting and Transformation Using CRISPR/Cas9 in Coccidioides

Current Protocols, Volume 6, Issue 9, September 2026.
Abstract Coccidioides posadasii and C. immitis are human fungal pathogens endemic to the American Southwest. C. posadasii and C. immitis are the causative agents of coccidioidomycosis, or Valley fever. They are pathogens of growing concern, as reported cases of coccidioidomycosis have increased 20‐fold in the last two decades.
Katrina M. Jackson, Matthew M. Morales, Edyta Szewczyk, Christina M. Homer, Ashley N. Itogawa, Rachel B. Brem, Anita Sil, Bridget M. Barker   +7 more
wiley   +1 more source

Imaging genome dynamics in real time with CRISPR-based technologies. [PDF]

Curr Opin Chem Biol
Adams BG, Wu J.
europepmc   +1 more source