Results 91 to 100 of about 3,905,348 (276)
Complex Dynamics of an Adnascent-Type Game Model
Discrete Dynamics in Nature and Society, 2008 The paper presents a nonlinear discrete game model for two oligopolistic firms whose products are adnascent. (In biology, the term adnascent has only one sense, “growing to or on something else,” e.g., “moss is an adnascent plant.” See Webster's Revised ...
Baogui Xin, Junhai Ma, Qin Gao
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Epigenomic and transcriptomic persistence of heat stress memory in strawberry (Fragaria vesca)
BMC Plant BiologyBackground In plants, epigenetic stress memory has so far been found to be largely transient. Here, we wanted to assess the heritability of heat stress-induced epigenetic and transcriptomic changes following woodland strawberry (Fragaria vesca ...
María-Estefanía López +2 more
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Neimark-Sacker Bifurcation in a Discrete-Time Financial System
Discrete Dynamics in Nature and Society, 2010 A discrete-time financial system is proposed by using forward Euler scheme. Based on explicit Neimark-Sacker bifurcation (also called Hopf bifurcation for map) criterion, normal form method and center manifold theory, the system's existence, stability ...
Baogui Xin, Tong Chen, Junhai Ma
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Group Reputation and the Dynamics of Statistical Discrimination [PDF]
Previous literature on statistical discrimination explained stereotypes based on the existence of multiple equilibria, in which principals have different self-confirming beliefs about different social groups (Arrow, 1973; Coate and Loury, 1993). However,
Kim, Young Chul, Loury, Glenn
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Multitask feature selection within structural datasets
Data-Centric EngineeringPopulation-based structural health monitoring (PBSHM) systems use data from multiple structures to make inferences of health states. An area of PBSHM that has recently been recognized for potential development is the use of multitask learning (MTL ...
Sarah Bee +4 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Social Segregation and the Dynamics of Group Inequality [PDF]
We explore the dynamics of group inequality when segregation of social networks places the initially less affluent group at a disadvantage in acquiring human capital.
Rajiv Sethi, Samuel Bowles
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