Results 21 to 30 of about 152,389 (315)
The role of mitochondria within injured neurons is an area of active interest since these organelles are vital for the production of cellular energy in the form of ATP.
Wendy M. Knowlton+6 more
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During the establishment of neural circuitry axons often need to cover long distances to reach remote targets. The stereotyped navigation of these axons defines the connectivity between brain regions and cellular subtypes.
Carlos Sánchez-Huertas, Eloísa Herrera
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An Integrated Cytoskeletal Model of Neurite Outgrowth
Neurite outgrowth underlies the wiring of the nervous system during development and regeneration. Despite a significant body of research, the underlying cytoskeletal mechanics of growth and guidance are not fully understood, and the relative ...
Kyle E. Miller+4 more
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Transcriptional Control of Axon Guidance at Midline Structures
The development of the nervous system is a time-ordered and multi-stepped process that includes neurogenesis and neuronal specification, axonal navigation, and circuits assembly.
Eloísa Herrera, Augusto Escalante
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Zebra stripes with high gyro-harmonic numbers [PDF]
Solar radio zebras are used in the determination of the plasma density and magnetic field in solar flare plasmas. Analyzing observed zebra stripes and assuming their generation by the double-plasma resonance (DPR) instability, high values of the gyro-harmonic number are found.
arxiv +1 more source
The nonuniqueness of the tangent cones at infinity of Ricci-flat manifolds [PDF]
It is shown by Colding and Minicozzi the uniqueness of the tangent cone at infinity of Ricci-flat manifolds with Euclidean volume growth which has at least one tangent cone at infinity with a smooth cross section. In this article we raise an example of the Ricci-flat manifold implying that the assumption for the volume growth in the above result is ...
arxiv +1 more source
To Stick or Not to Stick: The Multiple Roles of Cell Adhesion Molecules in Neural Circuit Assembly
Precise wiring of neural circuits is essential for brain connectivity and function. During development, axons respond to diverse cues present in the extracellular matrix or at the surface of other cells to navigate to specific targets, where they ...
Trevor Moreland, Fabienne E. Poulain
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Role of geometrical cues in neuronal growth [PDF]
Geometrical cues play an essential role in neuronal growth. Here, we quantify axonal growth on surfaces with controlled geometries and report a general stochastic approach that quantitatively describes the motion of growth cones. We show that axons display a strong directional alignment on micro-patterned surfaces when the periodicity of the patterns ...
arxiv +1 more source
Background While many molecules involved in axon guidance have been identified, the cellular and molecular mechanisms by which these molecules regulate growth cone morphology during axon outgrowth remain to be elucidated.
Lundquist Erik A+2 more
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Actin dynamics in growth cones [PDF]
The mechanism of actin incorporation and turnover in the nerve growth cone was examined by immunoelectron microscopy and low-light-level video microscopy of cultured neurons injected with biotin-labeled actin or fluorescently labeled actin. We first determined the sites of actin incorporation into the cytoskeleton of growth cones by immunoelectron ...
Nobutaka Hirokawa, Shigeo Okabe
openaire +2 more sources