Results 71 to 80 of about 400,493 (285)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo [PDF]

open access: yes, 1998
Tyrosine kinase signaling pathways are essential for process outgrowth and guidance during nervous system development. We have examined the roles of tyrosine kinase activity in programming growth cone guidance decisions in an intact nervous system in ...
Menon, Kaushiki P., Zinn, Kai
core  

Increasing radial solutions for Neumann problems without growth restrictions

open access: yes, 2011
We study the existence of positive increasing radial solutions for superlinear Neumann problems in the ball. We do not impose any growth condition on the nonlinearity at infinity and our assumptions allow for interactions with the spectrum.
Amann   +17 more
core   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

BDNF/trkB Induction of Calcium Transients through Cav2.2 Calcium Channels in Motoneurons Corresponds to F-actin Assembly and Growth Cone Formation on β2-Chain Laminin (221)

open access: yesFrontiers in Molecular Neuroscience, 2017
Spontaneous Ca2+ transients and actin dynamics in primary motoneurons correspond to cellular differentiation such as axon elongation and growth cone formation.
Benjamin Dombert   +6 more
doaj   +1 more source

Neuronal Signaling Involved in Neuronal Polarization and Growth: Lipid Rafts and Phosphorylation

open access: yesFrontiers in Molecular Neuroscience, 2020
Neuronal polarization and growth are developmental processes that occur during neuronal cell differentiation. The molecular signaling mechanisms involved in these events in in vivo mammalian brain remain unclear.
Michihiro Igarashi   +3 more
doaj   +1 more source

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

open access: yesAdvanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel   +6 more
wiley   +1 more source

PBF‐LB/M of Ti‐6Al‐4V: High‐Pressure Solution Treatment and Aging for Applications in a Sustainable Aerospace

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing (AM) allows great geometric freedom for lightweight components. As parts are progressively optimized exploiting potentials in AM leading in smaller material cross sections, high pressure solution treating and aging (STA) treatments show an enormous potential for strongly improving material properties.
Mika León Altmann   +4 more
wiley   +1 more source

Tribological Performance of 60NiTi Alloy Under Varying Contact Conditions and Elevated Temperatures in Linear Reciprocating Sliding

open access: yesAdvanced Engineering Materials, EarlyView.
This study investigates the tribological response of 60NiTi alloy under dry, water‐lubricated and high‐temperature conditions. The alloy exhibits decreasing wear volume and friction with increasing temperature due to the formation of protective oxide layers. The work clarifies dominant wear mechanisms and demonstrates the suitability of 60NiTi for high‐
Anthony Onyebuchi Okoani   +2 more
wiley   +1 more source

Parallels between the Developing Vascular and Neural Systems: Signaling Pathways and Future Perspectives for Regenerative Medicine

open access: yesAdvanced Science, 2021
Neurovascular disorders, which involve the vascular and nervous systems, are common. Research on such disorders usually focuses on either vascular or nervous components, without looking at how they interact.
Idoia Elorza Ridaura   +2 more
doaj   +1 more source

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