Results 71 to 80 of about 400,493 (285)
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo [PDF]
Tyrosine kinase signaling pathways are essential for process outgrowth and guidance during nervous system development. We have examined the roles of tyrosine kinase activity in programming growth cone guidance decisions in an intact nervous system in ...
Menon, Kaushiki P., Zinn, Kai
core
Increasing radial solutions for Neumann problems without growth restrictions
We study the existence of positive increasing radial solutions for superlinear Neumann problems in the ball. We do not impose any growth condition on the nonlinearity at infinity and our assumptions allow for interactions with the spectrum.
Amann +17 more
core +1 more source
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman +9 more
wiley +1 more source
Spontaneous Ca2+ transients and actin dynamics in primary motoneurons correspond to cellular differentiation such as axon elongation and growth cone formation.
Benjamin Dombert +6 more
doaj +1 more source
Neuronal Signaling Involved in Neuronal Polarization and Growth: Lipid Rafts and Phosphorylation
Neuronal polarization and growth are developmental processes that occur during neuronal cell differentiation. The molecular signaling mechanisms involved in these events in in vivo mammalian brain remain unclear.
Michihiro Igarashi +3 more
doaj +1 more source
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel +6 more
wiley +1 more source
Additive manufacturing (AM) allows great geometric freedom for lightweight components. As parts are progressively optimized exploiting potentials in AM leading in smaller material cross sections, high pressure solution treating and aging (STA) treatments show an enormous potential for strongly improving material properties.
Mika León Altmann +4 more
wiley +1 more source
This study investigates the tribological response of 60NiTi alloy under dry, water‐lubricated and high‐temperature conditions. The alloy exhibits decreasing wear volume and friction with increasing temperature due to the formation of protective oxide layers. The work clarifies dominant wear mechanisms and demonstrates the suitability of 60NiTi for high‐
Anthony Onyebuchi Okoani +2 more
wiley +1 more source
Neurovascular disorders, which involve the vascular and nervous systems, are common. Research on such disorders usually focuses on either vascular or nervous components, without looking at how they interact.
Idoia Elorza Ridaura +2 more
doaj +1 more source

