Results 71 to 80 of about 372,166 (319)
Directing growth cones of optic axons growing with laser scissors and laser tweezers [PDF]
, 2012 We have combined a laser scissors and a laser tweezers to study, (1) the response of nerve fiber growth cones to laserinduced damage on single axons, and (2) localized microfluidic flow generated by laser-driven spinning birefringent particles.
Berns, Michael W. +6 more
core +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
Cytoskeletal dynamics in growth-cone steering [PDF]
Journal of Cell Science, 2009 Interactions between dynamic microtubules and actin filaments are essential to a wide range of cell biological processes including cell division, motility and morphogenesis. In neuronal growth cones, interactions between microtubules and actin filaments in filopodia are necessary for growth cones to make a turn.
Geraldo, Sara, Gordon-Weeks, Phillip R.
openaire +4 more sources
Advanced Biology, EarlyView.Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers +3 more
wiley +1 more source
Nystatin Regulates Axonal Extension and Regeneration by Modifying the Levels of Nitric Oxide
Frontiers in Molecular Neuroscience, 2020 Nystatin is a pharmacological agent commonly used for the treatment of oral, mucosal and cutaneous fungal infections. Nystatin has also been extensively applied to study the cellular function of cholesterol-enriched structures because of its ability to ...
Cristina Roselló-Busquets +7 more
doaj +1 more source
Conical defects in growing sheets
, 2008 A growing or shrinking disc will adopt a conical shape, its intrinsic geometry characterized by a surplus angle $se$ at the apex. If growth is slow, the cone will find its equilibrium. Whereas this is trivial if $se
D. Fuchs +8 more
core +1 more source
The formin DAAM is required for coordination of the actin and microtubule cytoskeleton in axonal growth cones [PDF]
, 2017 Directed axonal growth depends on correct coordination of the actin and microtubule cytoskeleton in the growth cone. However, despite the relatively large number of proteins implicated in actin−microtubule crosstalk, the mechanisms whereby actin ...
Bugyi, Beata +10 more
core +2 more sources
Advanced Engineering Materials, EarlyView.Primary phases and a fatigue crack are studied in a forged blank of an aluminum alloy using synchrotron and laboratory X‐ray computed tomography. To image the crack, the fatigue test is interrupted, and a static tensile load is applied to open the crack.
Jakob Schröder +6 more
wiley +1 more source
Neuronal Signaling Involved in Neuronal Polarization and Growth: Lipid Rafts and Phosphorylation
Frontiers in Molecular Neuroscience, 2020 Neuronal polarization and growth are developmental processes that occur during neuronal cell differentiation. The molecular signaling mechanisms involved in these events in in vivo mammalian brain remain unclear.
Michihiro Igarashi +3 more
doaj +1 more source
Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo [PDF]
, 1998 Tyrosine kinase signaling pathways are essential for process outgrowth and guidance during nervous system development. We have examined the roles of tyrosine kinase activity in programming growth cone guidance decisions in an intact nervous system in ...
Menon, Kaushiki P., Zinn, Kai
core