Results 111 to 120 of about 2,830,094 (317)

c-Src Mediates Mitogenic Signals and Associates with Cytoskeletal Proteins upon Vascular Endothelial Growth Factor Stimulation in Kaposi’s Sarcoma Cells [PDF]

, 2000
Neru Munshi, Jerome E. Groopman, Parkash S. Gill, Ramesh K. Ganju   +3 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Corrigendum: Large-scale preparation of highly stable recombinant human acidic fibroblast growth factor in Escherichia coli BL21(DE3) plysS strain

Frontiers in Bioengineering and Biotechnology, 2022
Bingjie Yu, Bingjie Yu, Wenzhe Sun, Zhen Huang, Gang Sun, Le Li, Jiawei Gu, Mengying Zheng, Xiaokun Li, Xiaokun Li, ChangJu Chun, Qi Hui, Qi Hui, Xiaojie Wang, Xiaojie Wang   +14 more
doaj   +1 more source

The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain.

, 1991
Daniel E. Johnson, Jian Lu, Hubert C. Chen, Sabine Werner, L T Williams   +4 more
openalex   +2 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2.

, 1998
Valérie Fontaine, Norbert Kinkl, José‐Alain Sahel, H. Dreyfus, David Hicks   +4 more
openalex   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Epstein-Barr Virus Lytic Infection Is Required for Efficient Production of the Angiogenesis Factor Vascular Endothelial Growth Factor in Lymphoblastoid Cell Lines

, 2005
Gregory K. Hong, Pawan Kumar, Ling Wang, Blossom Damania, Margaret L. Gulley, Henri‐Jacques Delecluse, Peter J. Polverini, Shannon C. Kenney   +7 more
openalex   +1 more source

Relationship between endothelial progenitor cells and vascular endothelial growth factor and its variation with exercise [PDF]

, 2015
Juan Gagliardi, Neiva Maciel, José Luis Castellano, Osvaldo Masoli, Verónica Miksztowicz, Gabriela Berg, Emilsé Bermejo, M Lazzari, Ricardo J. Gelpi   +8 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source