Results 131 to 140 of about 14,563,375 (182)
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Growth factors and their receptors
Current Opinion in Cell Biology, 1989The growth of cells in culture is controlled by polypeptide hormones that stimulate or inhibit proliferation. More than 20 different growth factors have been extensively characterised, and the corresponding cDNAs have been cloned (Table 1). Several additional growth factors are known from their biological activities but have not yet been structurally ...
B, Westermark, C H, Heldin
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Neurological Sciences, 2003
Recent studies have provided new insights on the identity and mechanisms of action of growth factors implicated in myelination processes. Members of several different families of growth factors have been shown to affect oligodendrocyte survival, proliferation and differentiation and their manipulation in the experimental animal provides a means to ...
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Recent studies have provided new insights on the identity and mechanisms of action of growth factors implicated in myelination processes. Members of several different families of growth factors have been shown to affect oligodendrocyte survival, proliferation and differentiation and their manipulation in the experimental animal provides a means to ...
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Life Sciences, 1974
Publisher Summary This chapter discusses the structure of nerve growth factor (NGF). The amino acid sequence of mouse NGF exhibited significant structural relatedness with the family of insulins and proinsulins. The sequence of mouse NGF could be aligned with human proinsulin with only five deletions required to yield the maximum homology of 21 ...
L F, Boyd +6 more
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Publisher Summary This chapter discusses the structure of nerve growth factor (NGF). The amino acid sequence of mouse NGF exhibited significant structural relatedness with the family of insulins and proinsulins. The sequence of mouse NGF could be aligned with human proinsulin with only five deletions required to yield the maximum homology of 21 ...
L F, Boyd +6 more
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The International Journal of Developmental Biology, 1999
Signalling between cells in the developing vertebrate embryo is essential for normal embryonic development. In the mid 1970's, signal transduction research started at the Hubrecht Laboratory with special emphasis on analysis of the signalling mechanisms that direct cell proliferation and differentiation.
Laat, S.W. de +7 more
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Signalling between cells in the developing vertebrate embryo is essential for normal embryonic development. In the mid 1970's, signal transduction research started at the Hubrecht Laboratory with special emphasis on analysis of the signalling mechanisms that direct cell proliferation and differentiation.
Laat, S.W. de +7 more
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Growth factors and growth control
Current Opinion in Cell Biology, 1990Polypeptide growth factors are thought to govern a variety of physiological processes such as cell growth, differentiation, embryogenesis, hematopoiesis, and wound repair. Although it is well documented that growth factors are required for cell proliferation in tissue-culture systems, current knowledge of their in uivo functions is still meager.
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2019
Several cytokines have been used to treat autoimmune diseases, viral infections, and cancer and to regenerate the skin. In particular, interferons (INFs) have been used to treat cancer, hepatitis B and C, and multiple sclerosis, while interleukins (ILs) and tumor necrosis factors (TNFs) have been used in the management of different types of cancer ...
Silva, Ana Catarina, Lobo, J. M. Sousa
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Several cytokines have been used to treat autoimmune diseases, viral infections, and cancer and to regenerate the skin. In particular, interferons (INFs) have been used to treat cancer, hepatitis B and C, and multiple sclerosis, while interleukins (ILs) and tumor necrosis factors (TNFs) have been used in the management of different types of cancer ...
Silva, Ana Catarina, Lobo, J. M. Sousa
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Endocrinology of Growth and Growth Factors
Connective Tissue Research, 1995This review discusses normal growth patterns and the appropriate use of preprinted growth curves. The important roles of thyroid and growth hormone in the modulation of growth are delineated. I present an approach to the evaluation and proper management of children and adolescents with short stature and poor growth.
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Growth Hormone, Growth Factors and Hematopoiesis
Hormone Research, 2008Hypocellularity of primary lymphoid organs is a distinctive and reproducible characteristic of aged humans and animals. Similar changes have been reported in both hypophysectomized and dwarf rodents. In the bone marrow of these animals, there is an associated reduction in the number of erythroid, lymphoid and myeloid elements.
Kelley, K.W. +4 more
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Growth Factors and Growth Factor Inhibitors
1997This chapter will outline novel treatment strategies predicated on the modulation of growth factor or cytokine-mediated signal transduction pathways. Several excellent recent monographs have addressed this tissue from the point of view of inhibitors of individual pathway constituents (1,2).The current focus will be on defining the pathways potentially ...
Edward A. Sausville, Dan L. Longo
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Growth Factors: A scattering of factors
Current Biology, 1994Hepatocyte growth factor/scatter factor is a multifunctional growth factor with varied properties: more and more polypeptide factors are being discovered that share these characteristics.
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