Results 161 to 170 of about 2,830,094 (317)

Glutamate as a therapeutic strategy to promote liver regeneration

Clinical and Translational Medicine
María del Mar Rigual, Nabil Djouder
doaj   +1 more source

Role of Growth Factors in the Pathogenesis of Systemic-Sclerosis-Associated Fibrosis. [PDF]

Int J Mol Sci
Mendoza FA, Piera-Velazquez S, Jimenez SA.   +2 more
europepmc   +1 more source

PD-013 A study level meta-analysis of efficacy data from head-to-head first-line trials of epidermal growth factor receptor inhibitors (EGFRIs) vs bevacizumab in patients with metastatic colorectal cancer (mCRC) [PDF]

, 2015
Volker Heinemann, Fernando Rivera, Brianne O’Neill, Reija Koukakis, Jan-Henrik Terwey, Jean‐Yves Douillard   +5 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Insulin-Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes. [PDF]

J Diabetes Res
Gladych-Macioszek A, Ozegowska K, Radzicka-Mularczyk S, Sibiak R, Desoye G, Wender-Ozegowska E.   +5 more
europepmc   +1 more source

Dynamic expression of nerve growth factor and its receptor TrkA after subarachnoid hemorrhage in rat brain

, 2016
Jinning Song, Zunwei Liu, Long Sui, Bin-fei Zhang, Yong-lin Zhao, Xudong Ma, Hua Gu   +6 more
openalex   +1 more source

Role of Insulin-Like Growth Factor Binding Protein-2 and Its Limited Proteolysis in Neuroblastoma Cell Proliferation: Modulation by Transforming Growth Factor-  and Retinoic Acid [PDF]

, 1997
M. Menouny
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Cecal growth factors promote enteric neurosphere formation and hindgut colonization in the avian model. [PDF]

Front Cell Dev Biol
Soós Á, Szőcs E, Halasy V, Gecse Z, Mógor F, Jurenka C, Kocsis K, Mucksová J, Hejnar J, Nagy N.   +9 more
europepmc   +1 more source

Synthesis and Characterization of a Homogeneous Chemical Conjugate Between Basic Fibroblast Growth Factor and Saporin [PDF]

, 1995
Ying J. Buechler, Barbara A. Sosnowski, Kimberly D. Victor, Zahra Parandoosh, Stuart J. Bussell, Chun Shen, Marie Ryder, L. L. Houston   +7 more
openalex   +1 more source